GAD1

Description		glutamate decarboxylase 1
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GO Annotations	Cellular Component	Plasma Membrane Cell Cortex Vesicle Membrane Axon Terminus Presynaptic Active Zone Inhibitory Synapse Clathrin-sculpted Gamma-aminobutyric Acid Transport Vesicle Membrane
	Molecular Function	Glutamate Decarboxylase Activity Protein Binding Glutamate Binding Pyridoxal Phosphate Binding Protein-containing Complex Binding Protein N-terminus Binding
	Biological Process	Glutamate Catabolic Process Glutamate Decarboxylation To Succinate Chemical Synaptic Transmission Response To Xenobiotic Stimulus Gamma-aminobutyric Acid Biosynthetic Process Protein-pyridoxal-5-phosphate Linkage Social Behavior Locomotory Exploration Behavior Neurotransmitter Biosynthetic Process
Pathways		GABA synthesis GABA synthesis, release, reuptake and degradation MECP2 regulates transcription of genes involved in GABA signaling
Drugs		Pyridoxal phosphate Pyridoxal phosphate Glutamic acid
Diseases
GWAS		Menopause (age at onset) ( 26414677)
Interacting Genes		18 interacting genes: AGTRAP BASP1 CALM1 CMTM5 GAD2 HAAO KRT31 KRT40 KRTAP3-2 MAL2 PPP2CA PPP2CB PRKACA PRKCE STK3 TH TRIM23 TRIP6
Entrez ID		2571
HPRD ID		12011
Ensembl ID		ENSG00000128683
Uniprot IDs		A0A0S2Z3V5 Q8IVA8 Q99259
PDB IDs		2OKJ 3VP6
Enriched GO Terms of Interacting Partners?
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