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ISCU

Description iron-sulfur cluster assembly enzyme
Image
GO Annotations Cellular Component
  • Nucleus
  • Cytoplasm
  • Mitochondrion
  • Mitochondrial Matrix
  • Cytosol
Molecular Function
  • Iron Ion Binding
  • Protein Binding
  • Ferrous Iron Binding
  • 2 Iron, 2 Sulfur Cluster Binding
  • Molecular Adaptor Activity
Biological Process
  • Cellular Iron Ion Homeostasis
  • Iron-sulfur Cluster Assembly
  • Positive Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone
  • Positive Regulation Of Aconitate Hydratase Activity
  • Negative Regulation Of Iron Ion Import Across Plasma Membrane
Pathways
Drugs
Diseases
GWAS
  • Acne (severe) ( 24927181)
  • Intraocular pressure ( 29617998)
Interacting Genes 18 interacting genes: AGTRAP BANP CBY2 CCDC136 CCDC172 FAM9B GOLGA2 GOLGA6L9 HPRT1 IKZF1 JUN KRT34 KRT40 LNX1 MID2 NECAB2 NUP62 PICK1
Entrez ID 23479
HPRD ID 14828
Ensembl ID ENSG00000136003
Uniprot IDs A0A024RBI3 B1P7G3 B3KQ30 B4DNC9 Q9H1K1
PDB IDs 5KZ5 5WKP 5WLW 6NZU 6UXE 6W1D 6WI2 6WIH
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025