CUX2

Description		cut like homeobox 2
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GO Annotations	Cellular Component	Chromatin Nucleus Extracellular Exosome
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Short-term Memory Positive Regulation Of Gene Expression Positive Regulation Of Dendrite Morphogenesis Cognition Positive Regulation Of Synapse Assembly Positive Regulation Of Dendritic Spine Morphogenesis Cellular Response To Organic Substance Positive Regulation Of Excitatory Postsynaptic Potential
Pathways
Drugs
Diseases
GWAS		Activated partial thromboplastin time ( 29403010) Alanine aminotransferase levels ( 33339817) Alanine transaminase levels ( 29403010) Alcohol consumption (max-drinks) ( 29460428) Aspartate aminotransferase levels ( 33547301 29403010 33339817) Atrial fibrillation ( 28416822) Blood osmolality (transformed sodium) ( 28360221) Blood sugar levels ( 29403010) Blood urea nitrogen levels ( 29403010) Body mass index ( 26426971) Chloride levels ( 29403010) Coffee consumption ( 31345160 29367735) Colorectal cancer ( 26151821) Composite immunoglobulin trait (IgA x IgG/IgM) ( 28628107) Coronary artery disease ( 32469254) Coronary heart disease ( 23364394) Creatinine levels ( 29403010) Diastolic blood pressure ( 29403010 30487518) Epilepsy ( 33913524) Estimated glomerular filtration rate ( 31152163 30604766) Gamma glutamyl transferase levels ( 29403010 33339817) Glomerular filtration rate ( 29403010) Gout ( 25646370 27899376) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Hemoglobin levels ( 32327693) High density lipoprotein cholesterol levels ( 29403010 33339817) HOMA-B (corrected for HOMA-IR) ( 30369944) Hypertension ( 30487518) Idiopathic osteonecrosis of the femoral head ( 29118346) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Low density lipoprotein cholesterol levels ( 29403010 33339817) Mean arterial pressure ( 29403010 30487518) Mean arterial pressure x alcohol consumption interaction (2df test) ( 29912962) Mean corpuscular hemoglobin ( 29403010) Mean corpuscular hemoglobin concentration ( 29403010) Mean corpuscular volume ( 29403010) Pre-treatment viral load in HIV-1 infection ( 31219150) Pulse pressure ( 29403010 30487518) Red blood cell count ( 29403010) Renal overload gout ( 27899376) Renal underexcretion gout ( 27899376) Response to alcohol consumption (flushing response) ( 29460428) Serum uric acid levels ( 30993211 29403010 32514006) Smoking behaviour (cigarettes smoked per day) ( 31089300) Sodium levels ( 29403010) Systolic blood pressure ( 29403010) Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) Type 1 diabetes ( 22293688) Urate levels ( 31578528) Waist-hip ratio ( 34054925) Weight ( 34054925)
Interacting Genes		1 interacting genes: CSNK2A1
Entrez ID		23316
HPRD ID		10851
Ensembl ID		ENSG00000111249
Uniprot IDs		O14529
PDB IDs		1WH6 1WH8 1X2L
Enriched GO Terms of Interacting Partners?
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