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GPC4

Description glypican 4
Image No pdb structure
GO Annotations Cellular Component
  • Nucleus
  • Golgi Lumen
  • Plasma Membrane
  • External Side Of Plasma Membrane
  • Cell Surface
  • Lysosomal Lumen
  • Synapse
  • Collagen-containing Extracellular Matrix
  • Extracellular Exosome
  • Glutamatergic Synapse
  • Anchored Component Of Presynaptic Membrane
Molecular Function
  • Protein Binding
  • Coreceptor Activity Involved In Wnt Signaling Pathway, Planar Cell Polarity Pathway
Biological Process
  • Regulation Of Signal Transduction
  • Wnt Signaling Pathway
  • Cell Migration
  • Wnt Signaling Pathway, Planar Cell Polarity Pathway
  • Regulation Of Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane
  • Synaptic Membrane Adhesion
  • Regulation Of Protein Localization To Membrane
  • Regulation Of Presynapse Assembly
Pathways
  • A tetrasaccharide linker sequence is required for GAG synthesis
  • HS-GAG biosynthesis
  • HS-GAG biosynthesis
  • HS-GAG degradation
  • Defective B4GALT7 causes EDS, progeroid type
  • Defective B3GAT3 causes JDSSDHD
  • Defective EXT2 causes exostoses 2
  • Defective EXT1 causes exostoses 1, TRPS2 and CHDS
  • Defective B3GALT6 causes EDSP2 and SEMDJL1
  • Retinoid metabolism and transport
Drugs
Diseases
GWAS
Interacting Genes 11 interacting genes: ABHD17A ACP5 AKAP9 CCNC COL18A1 FGF2 MX1 PICK1 PTEN PTPRD PTPRF
Entrez ID 2239
HPRD ID 02160
Ensembl ID ENSG00000076716
Uniprot IDs O75487
PDB IDs
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025