FCGR3B

Description		Fc fragment of IgG receptor IIIb
Image
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane Secretory Granule Membrane Anchored Component Of Membrane Extracellular Exosome
	Molecular Function	Transmembrane Signaling Receptor Activity IgG Binding
	Biological Process	Immune Response Cell Surface Receptor Signaling Pathway Regulation Of Immune Response
Pathways		Post-translational modification: synthesis of GPI-anchored proteins Neutrophil degranulation
Drugs		Cetuximab Etanercept Human immunoglobulin G Gemtuzumab ozogamicin Muromonab Alemtuzumab Alefacept Natalizumab Palivizumab Daclizumab Catumaxomab Sarilumab
Diseases
GWAS		Basophil count ( 32888494) Basophil percentage of granulocytes ( 27863252) Basophil percentage of white cells ( 32888494 27863252) Blood protein levels ( 30072576 29875488) Hematocrit ( 32888494) Hemoglobin levels ( 32327693) Inflammatory bowel disease ( 28067908 23128233) Limited cutaneous systemic scleroderma ( 29293537) Monocyte count ( 32888494) Response to cyclophosphamide in systemic lupus erythematosus with lupus nephritis ( 26980576) Systemic lupus erythematosus ( 26502338) Systemic sclerosis (anti-centromere-positive) ( 29293537) Ulcerative colitis ( 28067908)
Interacting Genes		2 interacting genes: APCS IGHG1
Entrez ID		2215
HPRD ID		09951
Ensembl ID		ENSG00000162747
Uniprot IDs		A0A087WU90 A0A087WZR4 A0A3B3ISU3 O75015
PDB IDs		1E4J 1E4K 1FNL 1T83 1T89 6EAQ
Enriched GO Terms of Interacting Partners?
Tagcloud ?