ABCA3

Description		ATP binding cassette subfamily A member 3
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Lysosomal Membrane Late Endosome Plasma Membrane Integral Component Of Membrane Cytoplasmic Vesicle Membrane Multivesicular Body Membrane Lamellar Body Intracellular Membrane-bounded Organelle Alveolar Lamellar Body Lamellar Body Membrane Alveolar Lamellar Body Membrane
	Molecular Function	Lipid Transporter Activity ATP Binding ABC-type Xenobiotic Transporter Activity ATP Hydrolysis Activity ATPase-coupled Transmembrane Transporter Activity Phosphatidylcholine Transfer Activity Phosphatidylcholine Flippase Activity
	Biological Process	Xenobiotic Transmembrane Transport Lipid Transport Response To Xenobiotic Stimulus Positive Regulation Of Cholesterol Efflux Phospholipid Transport Lung Development Positive Regulation Of Protein Homooligomerization Lipid Translocation Xenobiotic Transport Surfactant Homeostasis Cellular Protein Metabolic Process Phosphatidylcholine Metabolic Process Phosphatidylglycerol Metabolic Process Xenobiotic Export Regulation Of Lipid Biosynthetic Process Response To Glucocorticoid Phospholipid Homeostasis Organelle Assembly Intermembrane Lipid Transfer Regulation Of Phosphatidylcholine Metabolic Process Positive Regulation Of Phospholipid Efflux Positive Regulation Of Phospholipid Transport
Pathways		ABC transporters in lipid homeostasis Defective ABCA3 causes SMDP3 Surfactant metabolism Defective ABCA3 causes SMDP3
Drugs
Diseases
GWAS		Birth weight ( 31043758) RR interval (tricyclic/tetracyclic antidepressant use interaction) ( 28039329) Triglyceride levels x SSRI defined daily dose interaction in schizophrenia or bipolar disorder ( 33824429) Trunk fat mass ( 28552196)
Interacting Genes		1 interacting genes: HTR2B
Entrez ID		21
HPRD ID		03369
Ensembl ID		ENSG00000167972
Uniprot IDs		Q4LE27 Q99758
PDB IDs
Enriched GO Terms of Interacting Partners?
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