DUSP4

Description		dual specificity phosphatase 4
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	Phosphoprotein Phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Binding Protein Tyrosine/threonine Phosphatase Activity Phosphatase Activity MAP Kinase Tyrosine/serine/threonine Phosphatase Activity Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity MAP Kinase Serine/threonine Phosphatase Activity
	Biological Process	Endoderm Formation Dephosphorylation Negative Regulation Of MAPK Cascade Negative Regulation Of ERK1 And ERK2 Cascade
Pathways		RAF-independent MAPK1/3 activation ERKs are inactivated Negative regulation of MAPK pathway
Drugs
Diseases
GWAS		Gestational age at birth (maternal effect) ( 28598419) Postoperative complication after cardiac surgery ( 30678657) Prostate cancer ( 33293427) Response to statin therapy ( 20339536) Spontaneous preterm birth (maternal effect) ( 28598419)
Interacting Genes		21 interacting genes: APP ATP1A3 CRMP1 GORASP2 GRIN1 GRIN2D IDO1 LYSMD1 LYSMD2 LZTS2 MAPK1 MAPK14 MAPK3 MAPK8 MAPK9 NOXA1 PLEKHF2 TEPSIN TRAF1 ZNF426 ZNF655
Entrez ID		1846
HPRD ID		04123
Ensembl ID		ENSG00000120875
Uniprot IDs		Q13115
PDB IDs		3EZZ
Enriched GO Terms of Interacting Partners?
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