DSG2

Description		desmoglein 2
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GO Annotations	Cellular Component	Cornified Envelope Plasma Membrane Cell-cell Junction Cell Surface Intercalated Disc Integral Component Of Membrane Cell Junction Desmosome Intracellular Membrane-bounded Organelle Extracellular Exosome
	Molecular Function	Calcium Ion Binding Cell Adhesion Molecule Binding Cell Adhesive Protein Binding Involved In Bundle Of His Cell-Purkinje Myocyte Communication
	Biological Process	Desmosome Organization Purkinje Myocyte Development Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Bundle Of His Cell-Purkinje Myocyte Adhesion Involved In Cell Communication Regulation Of Heart Rate By Cardiac Conduction Cell-cell Adhesion Regulation Of Ventricular Cardiac Muscle Cell Action Potential
Pathways		Apoptotic cleavage of cell adhesion proteins Keratinization Formation of the cornified envelope RAC2 GTPase cycle RHOG GTPase cycle RAC3 GTPase cycle
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488)
Interacting Genes		5 interacting genes: DSC1 DSC2 JUP PKP2 PKP3
Entrez ID		1829
HPRD ID		00516
Ensembl ID		ENSG00000046604
Uniprot IDs		Q14126
PDB IDs		2YQG 5ERD 5J5J 6QNT 6QNU 6SIT 7A7D 7AGF 7AGG
Enriched GO Terms of Interacting Partners?
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