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DHCR24
Description
24-dehydrocholesterol reductase
Image
No pdb structure
GO Annotations
Cellular Component
Golgi Membrane
Nucleus
Cytoplasm
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Cytosol
Cytoskeleton
Membrane
Integral Component Of Membrane
Molecular Function
Delta24(24-1) Sterol Reductase Activity
Protein Binding
Oxidoreductase Activity, Acting On The CH-CH Group Of Donors, NAD Or NADP As Acceptor
Enzyme Binding
Peptide Antigen Binding
Delta24-sterol Reductase Activity
FAD Binding
Biological Process
Cholesterol Biosynthetic Process
Apoptotic Process
Response To Oxidative Stress
Ras Protein Signal Transduction
Protein Localization
Steroid Metabolic Process
Negative Regulation Of Cell Population Proliferation
Response To Hormone
Tissue Development
Male Genitalia Development
Plasminogen Activation
Cholesterol Biosynthetic Process Via Desmosterol
Cholesterol Biosynthetic Process Via Lathosterol
Amyloid Precursor Protein Catabolic Process
Negative Regulation Of Apoptotic Process
Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Skin Development
Regulation Of Cell Cycle
Membrane Organization
Regulation Of Neuron Death
Pathways
Cholesterol biosynthesis via desmosterol
Cholesterol biosynthesis via lathosterol
Drugs
Diseases
GWAS
Visceral fat, circulating phospholipid PC(16:0/2:0) and white matter microstructure (shared variance) (
31900429
)
Interacting Genes
2 interacting genes:
CCR4
TP53
Entrez ID
1718
HPRD ID
05916
Ensembl ID
ENSG00000116133
Uniprot IDs
Q15392
PDB IDs
Enriched GO Terms of Interacting Partners
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