DEFB1

Description		defensin beta 1
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space Golgi Lumen Extrinsic Component Of Membrane Extracellular Exosome Sperm Midpiece Microvesicle
	Molecular Function	Protein Binding CCR6 Chemokine Receptor Binding Identical Protein Binding
	Biological Process	Innate Immune Response In Mucosa Chemotaxis Immune Response G Protein-coupled Receptor Signaling Pathway Response To Bacterium Antibacterial Humoral Response CAMP-mediated Signaling Calcium-mediated Signaling Using Intracellular Calcium Source Defense Response To Bacterium Innate Immune Response Defense Response To Gram-negative Bacterium Defense Response To Gram-positive Bacterium Positive Regulation Of Flagellated Sperm Motility Involved In Capacitation Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide
Pathways		Beta defensins Defensins
Drugs
Diseases
GWAS		Blood pressure ( 24954895) Blood protein levels ( 30072576 29875488) Dental caries (decayed and filled deciduous teeth) ( 31533690) Metabolite levels ( 23823483) Night sleep phenotypes ( 27126917) Plasma kynurenine levels in major depressive disorder ( 29317604) Plasma kynurenine to tryptophan ratio in major depressive disorder ( 29317604) Psoriatic arthritis ( 26626624)
Interacting Genes		6 interacting genes: ASPH CCR6 HAP1 MAP4K2 RIF1 VIM
Entrez ID		1672
HPRD ID		03634
Ensembl ID		ENSG00000164825
Uniprot IDs		P60022
PDB IDs		1E4S 1IJU 1IJV 1KJ5 2NLB 2NLC 2NLD 2NLE 2NLF 2NLG 2NLH 2NLP 2NLQ 2NLS 2PLZ
Enriched GO Terms of Interacting Partners?
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