CYP27B1

Description		cytochrome P450 family 27 subfamily B member 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Outer Membrane
	Molecular Function	Calcidiol 1-monooxygenase Activity Iron Ion Binding Heme Binding Secalciferol 1-monooxygenase Activity
	Biological Process	Vitamin Metabolic Process Calcium Ion Transport Negative Regulation Of Cell Population Proliferation Negative Regulation Of Calcidiol 1-monooxygenase Activity Positive Regulation Of Vitamin D 24-hydroxylase Activity Bone Mineralization Negative Regulation Of Cell Growth Regulation Of Bone Mineralization Response To Lipopolysaccharide Response To Vitamin D Response To Interferon-gamma Calcitriol Biosynthetic Process From Calciol Vitamin D Metabolic Process Vitamin D Catabolic Process Response To Estrogen Positive Regulation Of Keratinocyte Differentiation Decidualization Calcium Ion Homeostasis G1 To G0 Transition Positive Regulation Of Vitamin D Receptor Signaling Pathway
Pathways		Vitamin D (calciferol) metabolism Vitamins Defective CYP27B1 causes VDDR1A
Drugs		Alfacalcidol
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Multiple sclerosis ( 19525955 21833088)
Interacting Genes		8 interacting genes: ATF2 HOXC10 ITGB7 MARS1 MYL6 SMC3 TMEM50B TUT4
Entrez ID		1594
HPRD ID		02031
Ensembl ID		ENSG00000111012
Uniprot IDs		O15528
PDB IDs
Enriched GO Terms of Interacting Partners?
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