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SGO1

Description shugoshin 1
Image
GO Annotations Cellular Component
  • Chromosome, Centromeric Region
  • Kinetochore
  • Condensed Chromosome, Centromeric Region
  • Spindle Pole
  • Nucleoplasm
  • Centrosome
  • Cytosol
Molecular Function
  • Protein Binding
  • Kinase Binding
Biological Process
  • Mitotic Sister Chromatid Segregation
  • Chromosome Segregation
  • Attachment Of Spindle Microtubules To Kinetochore
  • Centriole-centriole Cohesion
  • Meiotic Chromosome Segregation
  • Homologous Chromosome Segregation
  • Meiotic Sister Chromatid Cohesion
  • Cell Division
  • Mitotic Sister Chromatid Cohesion, Centromeric
Pathways
  • Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
  • Separation of Sister Chromatids
  • Resolution of Sister Chromatid Cohesion
  • RHO GTPases Activate Formins
  • Mitotic Prometaphase
  • EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS
Interacting Genes 22 interacting genes: CDCA8 ICOSLG LRRC59 POLE4 PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E PRKDC RPL10A RPL28 RPL7 RPL7A RPLP1 SET XRCC5 XRCC6
Entrez ID 151648
HPRD ID 12377
Ensembl ID ENSG00000129810
Uniprot IDs A0A024R2J4 B5BUA4 Q5FBB7
PDB IDs 3FGA 3Q6S 4A0I
Enriched GO Terms of Interacting Partners?
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