CP

Description		ceruloplasmin
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Lysosomal Membrane Endoplasmic Reticulum Lumen Plasma Membrane Extracellular Exosome Blood Microparticle
	Molecular Function	Ferroxidase Activity Copper Ion Binding Oxidoreductase Activity Chaperone Binding
	Biological Process	Copper Ion Transport Iron Ion Transport Cellular Iron Ion Homeostasis Iron Ion Homeostasis
Pathways		Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Metal ion SLC transporters Defective SLC40A1 causes hemochromatosis 4 (HFE4) (macrophages) Defective CP causes aceruloplasminemia (ACERULOP) Post-translational protein phosphorylation Iron uptake and transport
Drugs		Calcium Iron Zinc Silver Zinc acetate Ferrous gluconate Ferrous succinate Ferrous ascorbate Ferrous fumarate Ferrous glycine sulfate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Subcutaneous adipose tissue ( 22589738)
Interacting Genes		8 interacting genes: ATP7A BTRC GAST HSP90AA1 LTF MPO PLG PROC
Entrez ID		1356
HPRD ID		00317
Ensembl ID		ENSG00000047457
Uniprot IDs		A5PL27 P00450
PDB IDs		1KCW 2J5W 4EJX 4ENZ
Enriched GO Terms of Interacting Partners?
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