CGAS

Description		cyclic GMP-AMP synthase
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GO Annotations	Cellular Component	Nucleus Cytosol Plasma Membrane Site Of Double-strand Break
	Molecular Function	DNA Binding Chromatin Binding Double-stranded DNA Binding Protein Binding ATP Binding GTP Binding Phosphatidylinositol-4,5-bisphosphate Binding Metal Ion Binding 2',3'-cyclic GMP-AMP Synthase Activity
	Biological Process	Activation Of Innate Immune Response Positive Regulation Of Defense Response To Virus By Host Regulation Of Immunoglobulin Production DNA Repair Cellular Response To DNA Damage Stimulus Determination Of Adult Lifespan Positive Regulation Of CGMP-mediated Signaling Positive Regulation Of Type I Interferon Production Paracrine Signaling Positive Regulation Of CAMP-mediated Signaling Innate Immune Response Regulation Of T Cell Activation Defense Response To Virus Cellular Response To Exogenous DsRNA Negative Regulation Of Double-strand Break Repair Via Homologous Recombination Positive Regulation Of Cellular Senescence
Pathways		STING mediated induction of host immune responses
Drugs
Diseases
GWAS
Interacting Genes		1 interacting genes: RNF185
Entrez ID		115004
HPRD ID		12857
Ensembl ID		ENSG00000164430
Uniprot IDs		Q8N884
PDB IDs		4KM5 4LEV 4LEW 4MKP 4O67 4O68 4O69 5V8O 5VDO 5VDP 5VDQ 5VDR 5VDS 5VDT 5VDU 5VDV 5VDW 6CT9 6CTA 6EDB 6EDC 6LRC 6LRE 6LRI 6LRJ 6LRK 6LRL 6MJU 6MJW 6MJX 6NAO 6NFG 6NFO 6O47 6Y5D 6Y5E 7C0M 7CCQ 7CCR
Enriched GO Terms of Interacting Partners?
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