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DCTN3

Description dynactin subunit 3
Image No pdb structure
GO Annotations Cellular Component
  • Kinetochore
  • Nucleolus
  • Centrosome
  • Spindle
  • Cytosol
  • Dynactin Complex
  • Microtubule
  • Midbody
  • Cleavage Furrow
  • Perinuclear Region Of Cytoplasm
Molecular Function
  • Structural Molecule Activity
  • Protein Binding
Biological Process
  • Mitotic Cell Cycle
  • Microtubule-based Process
  • Cytoskeleton-dependent Cytokinesis
Pathways
  • MHC class II antigen presentation
  • Regulation of PLK1 Activity at G2/M Transition
  • HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand
  • Loss of Nlp from mitotic centrosomes
  • Recruitment of mitotic centrosome proteins and complexes
  • Loss of proteins required for interphase microtubule organization from the centrosome
  • Recruitment of NuMA to mitotic centrosomes
  • Anchoring of the basal body to the plasma membrane
  • COPI-mediated anterograde transport
  • COPI-independent Golgi-to-ER retrograde traffic
  • AURKA Activation by TPX2
Drugs
Diseases
GWAS
Interacting Genes 13 interacting genes: ATXN1 CCL19 CCL21 DCTN1 GSK3B KRT34 NUP54 PBX2 PITX1 TRIM55 TRIP13 USHBP1 VPS37C
Entrez ID 11258
HPRD ID 06303
Ensembl ID ENSG00000137100
Uniprot IDs O75935 X6RLR1
PDB IDs
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025