ADAMTS6

Description		ADAM metallopeptidase with thrombospondin type 1 motif 6
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Matrix
	Molecular Function	Metalloendopeptidase Activity Metallopeptidase Activity Metal Ion Binding
	Biological Process	Kidney Development Cardiac Septum Development Proteolysis Extracellular Matrix Organization Aorta Development Coronary Vasculature Development
Pathways		Defective B3GALTL causes Peters-plus syndrome (PpS) O-glycosylation of TSR domain-containing proteins
Drugs
Diseases
GWAS		Body shape index ( 34021172) Brain morphology (MOSTest) ( 32665545) Central corneal thickness ( 32528159 31798171 29760442) Corneal structure ( 23291589) Corpus callosum anterior volume ( 31530798) Cortical surface area (MOSTest) ( 32665545) Feeling tense ( 29500382) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Heel bone mineral density ( 30598549) Height ( 31562340) Inguinal hernia ( 26686553) Intraocular pressure ( 29617998 29785010 30054594) LDL levels x SSRI defined daily dose interaction in schizophrenia or bipolar disorder ( 33824429) Non-response to bupropion and depression ( 27622933) Osteosarcoma ( 23727862) Schizophrenia ( 23212062) Subcortical volume (MOSTest) ( 32665545) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		6 interacting genes: ARSB CD180 CDK7 ERCC8 PART1 SNTA1
Entrez ID		11174
HPRD ID		05421
Ensembl ID		ENSG00000049192
Uniprot IDs		Q5IR90 Q9UKP5
PDB IDs
Enriched GO Terms of Interacting Partners?
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