KIF2C

Description		kinesin family member 2C
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GO Annotations	Cellular Component	Chromosome, Centromeric Region Kinetochore Nucleus Centrosome Spindle Cytosol Kinesin Complex Microtubule Cytoplasmic Microtubule Microtubule Cytoskeleton Membrane Microtubule Plus-end
	Molecular Function	Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATP Hydrolysis Activity Centromeric DNA Binding Microtubule Plus-end Binding
	Biological Process	Microtubule-based Movement Microtubule Depolymerization Mitotic Metaphase Plate Congression Establishment Or Maintenance Of Microtubule Cytoskeleton Polarity Cell Division Metaphase Plate Congression Attachment Of Mitotic Spindle Microtubules To Kinetochore Regulation Of Chromosome Segregation
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins COPI-dependent Golgi-to-ER retrograde traffic Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation Kinesins
Drugs		Phosphoaminophosphonic Acid-Adenylate Ester
Diseases
GWAS
Interacting Genes		14 interacting genes: APP AURKA CENPH CSNK2B DRD4 H3-4 KDM4A NDEL1 PLK1 PMPCA SUMO2 TOMM70 VHL ZNF566
Entrez ID		11004
HPRD ID		05172
Ensembl ID		ENSG00000142945
Uniprot IDs		A0A140VKF1 B7Z6Q6 B7Z7M6 Q99661
PDB IDs		2HEH 4UBF 4Y05 5MIO
Enriched GO Terms of Interacting Partners?
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