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CLP1

Description cleavage factor polyribonucleotide kinase subunit 1
Image No pdb structure
GO Annotations Cellular Component
  • TRNA-intron Endonuclease Complex
  • Nucleus
  • Nucleoplasm
  • Cytosol
  • MRNA Cleavage Factor Complex
Molecular Function
  • Protein Binding
  • ATP Binding
  • Polydeoxyribonucleotide 5'-hydroxyl-kinase Activity
  • Polynucleotide 5'-hydroxyl-kinase Activity
  • Polydeoxyribonucleotide Kinase Activity
  • Polyribonucleotide 5'-hydroxyl-kinase Activity
Biological Process
  • MRNA Polyadenylation
  • TRNA Splicing, Via Endonucleolytic Cleavage And Ligation
  • RNA Processing
  • Phosphorylation
  • Cerebellar Cortex Development
  • Targeting Of MRNA For Destruction Involved In RNA Interference
  • MRNA 3'-end Processing
  • SiRNA Loading Onto RISC Involved In RNA Interference
Pathways
  • tRNA processing in the nucleus
  • mRNA Splicing - Major Pathway
  • mRNA 3'-end processing
  • RNA Polymerase II Transcription Termination
  • Processing of Intronless Pre-mRNAs
Drugs
Diseases
GWAS
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Mean corpuscular hemoglobin ( 32888494)
  • Mean corpuscular volume ( 32888494)
  • Neuroticism ( 29255261)
  • Schizophrenia ( 25056061 29483656)
Interacting Genes 17 interacting genes: APP CEP164 CPSF3 CREB3 DAGLB FGF16 FTO HCFC1 MEOX2 MESD NUDT21 PCMT1 PRR3 PSMB5 SNF8 TSEN54 YJU2B
Entrez ID 10978
HPRD ID 16382
Ensembl ID ENSG00000172409
Uniprot IDs Q92989
PDB IDs
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025