USP19

Description		ubiquitin specific peptidase 19
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GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Cytosol Integral Component Of Membrane
	Molecular Function	Thiol-dependent Deubiquitinase Protein Binding Ubiquitin Protein Ligase Binding Metal Ion Binding Hsp90 Protein Binding Lys48-specific Deubiquitinase Activity
	Biological Process	Protein Deubiquitination Ubiquitin-dependent ERAD Pathway Regulation Of Protein Stability Response To Endoplasmic Reticulum Stress Negative Regulation Of Skeletal Muscle Tissue Development Protein Stabilization Protein K48-linked Deubiquitination Positive Regulation Of Cell Cycle Process Regulation Of Cellular Response To Hypoxia Negative Regulation Of Proteasomal Protein Catabolic Process Regulation Of ERAD Pathway
Pathways		Ub-specific processing proteases
Drugs
Diseases
GWAS		Blood protein levels ( 28240269) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Smoking cessation ( 33082346) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 28067908)
Interacting Genes		13 interacting genes: BIRC3 CKAP5 ECEL1 FLNA HIF1A HNRNPAB HSP90AA1 LAMTOR4 RNF2 SIAH1 SIAH2 SNRNP200 UBC
Entrez ID		10869
HPRD ID		18278
Ensembl ID		ENSG00000172046
Uniprot IDs		O94966
PDB IDs		1WH0 4X3G 6K7W 6KHV 6KQV
Enriched GO Terms of Interacting Partners?
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