TNFSF13B

Description		TNF superfamily member 13b
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm Plasma Membrane Focal Adhesion Integral Component Of Membrane Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm
	Molecular Function	Signaling Receptor Binding Cytokine Activity Tumor Necrosis Factor Receptor Binding Protein Binding Receptor Ligand Activity
	Biological Process	B Cell Homeostasis Positive Regulation Of Germinal Center Formation Immune Response Signal Transduction B Cell Differentiation Positive Regulation Of B Cell Proliferation T Cell Costimulation B Cell Costimulation Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of T Cell Proliferation
Pathways		TNFR2 non-canonical NF-kB pathway TNFs bind their physiological receptors TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway
Drugs		1,4-Dioxane Belimumab
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Blood protein levels ( 30072576) HDL cholesterol levels ( 32203549) IgG levels ( 28628107) Metabolite levels ( 23823483) Monocyte count ( 32888494) Monocyte percentage of white cells ( 32888494) Myeloid white cell count ( 27863252) Non-albumin protein levels ( 29403010) Platelet count ( 32888494 27863252) Platelet distribution width ( 32888494 27863252) Plateletcrit ( 32888494 27863252) Spleen volume ( 34128465) Tonsillectomy ( 27182965 28928442) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683) White blood cell count ( 27863252)
Interacting Genes		5 interacting genes: APP TNFRSF13B TNFRSF13C TNFRSF17 TNFSF13
Entrez ID		10673
HPRD ID		04914
Ensembl ID		ENSG00000102524
Uniprot IDs		A0A0U5J7Q1 Q9Y275
PDB IDs		1JH5 1KD7 1KXG 1OQD 1OQE 1OSG 3V56 4V46 4ZCH 5Y9J 6FXN
Enriched GO Terms of Interacting Partners?
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