ADAR

Description		adenosine deaminase RNA specific
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Membrane Supraspliceosomal Complex
	Molecular Function	DNA Binding RNA Binding Double-stranded RNA Binding Double-stranded RNA Adenosine Deaminase Activity Protein Binding TRNA-specific Adenosine Deaminase Activity Metal Ion Binding
	Biological Process	Osteoblast Differentiation Hematopoietic Progenitor Cell Differentiation Somatic Diversification Of Immune Receptors Via Somatic Mutation Adenosine To Inosine Editing RNA Processing MRNA Processing Response To Virus Base Conversion Or Substitution Editing Erythrocyte Differentiation Pre-miRNA Processing MiRNA Loading Onto RISC Involved In Gene Silencing By MiRNA Response To Interferon-alpha Negative Regulation Of Apoptotic Process Negative Regulation Of Protein Kinase Activity By Regulation Of Protein Phosphorylation Positive Regulation Of Viral Genome Replication Innate Immune Response Defense Response To Virus Definitive Hemopoiesis Negative Regulation Of Type I Interferon-mediated Signaling Pathway Hematopoietic Stem Cell Homeostasis Cellular Response To Virus Negative Regulation Of RNA Interference
Pathways		C6 deamination of adenosine Formation of editosomes by ADAR proteins Interferon alpha/beta signaling
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) C-reactive protein levels or triglyceride levels (pleiotropy) ( 27286809) Cerebrospinal fluid levels of Alzheimer's disease-related proteins ( 25340798) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Interleukin-6 levels ( 33517400) Lung cancer ( 28604730) Prostate cancer ( 23535732) Squamous cell lung carcinoma ( 28604730)
Interacting Genes		6 interacting genes: ERG HDLBP PTEN TGM2 UBE2I XPO1
Entrez ID		103
HPRD ID		07528
Ensembl ID		ENSG00000160710
Uniprot IDs		P55265
PDB IDs		1QBJ 1QGP 1XMK 2ACJ 2GXB 2L54 2MDR 3F21 3F22 3F23 3IRQ 3IRR 5ZU1 5ZUO 5ZUP 7C0I
Enriched GO Terms of Interacting Partners?
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