gpx4 - New-wiki

Novel	Interactant Symbol	Name	Associated Pathways Hide	Binding Drugs Hide	Associated Diseases Hide
Novel	APBA3	amyloid beta precursor protein binding family A member 3	Neurexins and neuroligins
Novel	EGR4	early growth response 4	NGF-stimulated transcription
Novel	FUT5	fucosyltransferase 5	Lewis blood group biosynthesis
Novel	GAMT	guanidinoacetate N-methyltransferase	Creatine metabolism Transcriptional Regulation by MECP2	Creatine Guanidine S-adenosyl-L-homocysteine Glycocyamine Phosphocreatine	Creatine deficiency syndrome, including: Arginine:glycine amidinotransferase deficiency (AGAT deficiency); Guanidinoacetate methyltransferase deficiency (GAMT deficiency); X-linked creatine deficiency syndrome (XL-CDS) Guanidinoacetate methyltransferase (GAMT) deficiency
Novel	GTF2F1	general transcription factor IIF subunit 1	Formation of RNA Pol II elongation complex Formation of the Early Elongation Complex Formation of HIV elongation complex in the absence of HIV Tat Formation of the HIV-1 Early Elongation Complex RNA Pol II CTD phosphorylation and interaction with CE during HIV infection HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome Formation of HIV-1 elongation complex containing HIV-1 Tat Formation of HIV-1 elongation complex containing HIV-1 Tat Pausing and recovery of Tat-mediated HIV elongation Abortive elongation of HIV-1 transcript in the absence of Tat Tat-mediated HIV elongation arrest and recovery Tat-mediated elongation of the HIV-1 transcript HIV elongation arrest and recovery Pausing and recovery of HIV elongation Viral Messenger RNA Synthesis RNA Polymerase II Pre-transcription Events TP53 Regulates Transcription of DNA Repair Genes FGFR2 alternative splicing RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes mRNA Capping mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Elongation RNA Polymerase II Transcription Initiation And Promoter Clearance RNA Pol II CTD phosphorylation and interaction with CE Signaling by FGFR2 IIIa TM Estrogen-dependent gene expression
Novel	MATK	megakaryocyte-associated tyrosine kinase	Downregulation of ERBB2 signaling	Fostamatinib
Novel	ZNF197	zinc finger protein 197	Generic Transcription Pathway
	MAPK13	mitogen-activated protein kinase 13	NOD1/2 Signaling Pathway p38MAPK events DSCAM interactions VEGFA-VEGFR2 Pathway	Minocycline KC706 Fostamatinib
	PARK7	Parkinsonism associated deglycase	SUMOylation of transcription cofactors Chaperone Mediated Autophagy Late endosomal microautophagy Aggrephagy Aggrephagy	Copper	Parkinson's disease (PD)
	PRDX6	peroxiredoxin 6	Detoxification of Reactive Oxygen Species Neutrophil degranulation	2-(N-morpholino)ethanesulfonic acid Copper

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