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Novel |
ACRV1 |
acrosomal vesicle protein 1 |
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Novel |
AP1G1 |
adaptor related protein complex 1 subunit gamma 1 |
- Nef mediated downregulation of MHC class I complex cell surface expression
- MHC class II antigen presentation
- Lysosome Vesicle Biogenesis
- Golgi Associated Vesicle Biogenesis
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Novel |
CNN1 |
calponin 1 |
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Novel |
DHPS |
deoxyhypusine synthase |
- Hypusine synthesis from eIF5A-lysine
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- 1-Guanidinium-7-Aminoheptane
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Novel |
LDB1 |
LIM domain binding 1 |
- RUNX1 regulates transcription of genes involved in differentiation of HSCs
- Regulation of expression of SLITs and ROBOs
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Novel |
NOTCH3 |
notch receptor 3 |
- Pre-NOTCH Processing in the Endoplasmic Reticulum
- Pre-NOTCH Transcription and Translation
- Pre-NOTCH Processing in Golgi
- Pre-NOTCH Processing in Golgi
- Notch-HLH transcription pathway
- Defective LFNG causes SCDO3
- NOTCH3 Activation and Transmission of Signal to the Nucleus
- NOTCH3 Activation and Transmission of Signal to the Nucleus
- NOTCH3 Intracellular Domain Regulates Transcription
- NOTCH3 Intracellular Domain Regulates Transcription
- Noncanonical activation of NOTCH3
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- Cerebral autosomal dominant arteriopathy with subcortical infarcts and leucoencephalopathy (CADASIL)
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ABHD16A |
abhydrolase domain containing 16A, phospholipase |
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ACSS2 |
acyl-CoA synthetase short chain family member 2 |
- Transcriptional activation of mitochondrial biogenesis
- Ethanol oxidation
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ATR |
ATR serine/threonine kinase |
- Meiotic synapsis
- Activation of ATR in response to replication stress
- Regulation of HSF1-mediated heat shock response
- HDR through Single Strand Annealing (SSA)
- Processing of DNA double-strand break ends
- Presynaptic phase of homologous DNA pairing and strand exchange
- Fanconi Anemia Pathway
- TP53 Regulates Transcription of DNA Repair Genes
- Regulation of TP53 Activity through Phosphorylation
- G2/M DNA damage checkpoint
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- Alveolar rhabdomyosarcoma
- Seckel syndrome
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CSNK2B |
casein kinase 2 beta |
- Synthesis of PC
- WNT mediated activation of DVL
- Condensation of Prometaphase Chromosomes
- Signal transduction by L1
- Neutrophil degranulation
- Regulation of TP53 Activity through Phosphorylation
- Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
- Receptor Mediated Mitophagy
- RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
- Regulation of PTEN stability and activity
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DCP1A |
decapping mRNA 1A |
- mRNA decay by 5' to 3' exoribonuclease
- Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA
- Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA
- Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
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DCP2 |
decapping mRNA 2 |
- ATF4 activates genes in response to endoplasmic reticulum stress
- mRNA decay by 5' to 3' exoribonuclease
- Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA
- Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA
- KSRP (KHSRP) binds and destabilizes mRNA
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DXO |
decapping exoribonuclease |
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EIF3A |
eukaryotic translation initiation factor 3 subunit A |
- L13a-mediated translational silencing of Ceruloplasmin expression
- Translation initiation complex formation
- Formation of a pool of free 40S subunits
- Formation of the ternary complex, and subsequently, the 43S complex
- Ribosomal scanning and start codon recognition
- GTP hydrolysis and joining of the 60S ribosomal subunit
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EIF3B |
eukaryotic translation initiation factor 3 subunit B |
- L13a-mediated translational silencing of Ceruloplasmin expression
- Translation initiation complex formation
- Formation of a pool of free 40S subunits
- Formation of the ternary complex, and subsequently, the 43S complex
- Ribosomal scanning and start codon recognition
- GTP hydrolysis and joining of the 60S ribosomal subunit
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EIF4A3 |
eukaryotic translation initiation factor 4A3 |
- ISG15 antiviral mechanism
- Transport of Mature mRNA derived from an Intron-Containing Transcript
- Deadenylation of mRNA
- mRNA Splicing - Major Pathway
- mRNA 3'-end processing
- RNA Polymerase II Transcription Termination
- Regulation of expression of SLITs and ROBOs
- Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
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EXOSC2 |
exosome component 2 |
- ATF4 activates genes in response to endoplasmic reticulum stress
- mRNA decay by 3' to 5' exoribonuclease
- Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA
- Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA
- KSRP (KHSRP) binds and destabilizes mRNA
- Major pathway of rRNA processing in the nucleolus and cytosol
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EXOSC4 |
exosome component 4 |
- ATF4 activates genes in response to endoplasmic reticulum stress
- mRNA decay by 3' to 5' exoribonuclease
- Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA
- Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA
- KSRP (KHSRP) binds and destabilizes mRNA
- Major pathway of rRNA processing in the nucleolus and cytosol
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GNPTG |
N-acetylglucosamine-1-phosphate transferase subunit gamma |
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- Mucolipidosis II and III, including: Mucolipidosis II / I-cell disease; Mucolipidosis III A / Pseudo-Hurler polydystrophy; Mucolipidosis III C
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HIRA |
histone cell cycle regulator |
- Formation of Senescence-Associated Heterochromatin Foci (SAHF)
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