Search Results for: TSNARE1

Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
Novel TOP1MT DNA topoisomerase I mitochondrial
  • Irinotecan
  • Topotecan
Novel ZNF707 zinc finger protein 707
  • Generic Transcription Pathway
CD79A CD79a molecule
  • CD22 mediated BCR regulation
  • Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
  • Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
  • Agammaglobulinemias, including the following six diseases: X-linked agammaglobulinemia (Bruton's agammaglobulinemia, XLA); IgM heavy chain gene deletions; Ig-alpha defect; Autosomal recessive agammaglobulinaemia; B cell-linker protein (BLNK) deficiency; Leucine-rich repeat-containing 8
CNIH4 cornichon family AMPA receptor auxiliary protein 4
CYB561 cytochrome b561
DYNLL1 dynein light chain LC8-type 1
  • Activation of BIM and translocation to mitochondria
  • Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
  • Macroautophagy
  • MHC class II antigen presentation
  • Separation of Sister Chromatids
  • Resolution of Sister Chromatid Cohesion
  • Regulation of PLK1 Activity at G2/M Transition
  • HSP90 chaperone cycle for steroid hormone receptors (SHR)
  • Loss of Nlp from mitotic centrosomes
  • Recruitment of mitotic centrosome proteins and complexes
  • Loss of proteins required for interphase microtubule organization from the centrosome
  • Recruitment of NuMA to mitotic centrosomes
  • Anchoring of the basal body to the plasma membrane
  • Intraflagellar transport
  • RHO GTPases Activate Formins
  • Neutrophil degranulation
  • COPI-mediated anterograde transport
  • COPI-independent Golgi-to-ER retrograde traffic
  • Mitotic Prometaphase
  • AURKA Activation by TPX2
  • HCMV Early Events
  • Aggrephagy
  • Aggrephagy
  • EML4 and NUDC in mitotic spindle formation
EBP EBP cholestenol delta-isomerase
  • Cholesterol biosynthesis via desmosterol
  • Cholesterol biosynthesis via lathosterol
  • Tamoxifen
ELOVL4 ELOVL fatty acid elongase 4
  • Synthesis of very long-chain fatty acyl-CoAs
  • Omega-3-carboxylic acids
  • Stargardt disease (STGD); Fundus flavimaculatus
ELOVL5 ELOVL fatty acid elongase 5
  • Linoleic acid (LA) metabolism
  • alpha-linolenic acid (ALA) metabolism
  • Synthesis of very long-chain fatty acyl-CoAs
  • alpha-Linolenic acid
GPR152 G protein-coupled receptor 152
JAGN1 jagunal homolog 1
LEPROTL1 leptin receptor overlapping transcript like 1
LMNA lamin A/C
  • XBP1(S) activates chaperone genes
  • Signaling by BRAF and RAF fusions
  • Restrictive dermopathy
  • Emery-Dreifuss muscular dystrophy
  • Dilated cardiomyopathy (DCM)
  • Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy
  • Mandibuloacral dysplasia
  • Congenital muscular dystrophies (CMD/MDC), including: Merosin-deficient CMD (MDC1A); Ullrich CMD (UCMD); Integrin alpha7-deficient CMD; CMD with joint hyperlaxity (CMDH); CMD with epidermolysis bullosa; Walker-Warburg syndrome (WWS); Muscle-eye-brain disease (MEB); Fukuyama CMD (FCMD); CMD with muscle hypertrophy (MDC1C); CMD with severe intellectual impairment and abnormal glycosylation (MDC1D); Rigid spine syndrome (RSS); LMNA-deficient CMD; CMD with respiratory failure and muscle hypertrophy (MDC1B); Bethlem myopathy
  • Limb-girdle muscular dystrophy (LGMD)
  • Familial partial lipodystrophy (FPL), including the following four diseases: Kobberling-type lipodystrophy (FPLD1); Dunnigan-type lipodystrophy (FPLD2); Dunnigan-like lipodystrophy (FPLD3); AKT2 associated lipodystrophy
  • Hutchinson-Gilford progeria syndrome
MFSD14B major facilitator superfamily domain containing 14B
REEP4 receptor accessory protein 4
  • Olfactory Signaling Pathway
RETREG3 reticulophagy regulator family member 3
SEC11C SEC11 homolog C, signal peptidase complex subunit
  • SRP-dependent cotranslational protein targeting to membrane
  • Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)
  • Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
  • Synthesis, secretion, and deacylation of Ghrelin
SLC10A6 solute carrier family 10 member 6
  • Transport of bile salts and organic acids, metal ions and amine compounds
SLC35C2 solute carrier family 35 member C2
SNAP29 synaptosome associated protein 29
  • Neutrophil degranulation
  • Intra-Golgi traffic
  • Cerebral dysgenesis, neuropathy, ichthyosis, and palmoplantar keratoderma syndrome; CEDNIK syndrome

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