TMEM97 - New-wiki

Novel	Interactant Symbol	Name	Associated Pathways Hide	Binding Drugs Hide	Associated Diseases Hide
Novel	ADCYAP1R1	ADCYAP receptor type I	NGF-independant TRKA activation G alpha (s) signalling events Glucagon-type ligand receptors ADORA2B mediated anti-inflammatory cytokines production
Novel	CRLF3	cytokine receptor like factor 3
Novel	ERAL1	Era like 12S mitochondrial rRNA chaperone 1	Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination
Novel	ORC1	origin recognition complex subunit 1	E2F-enabled inhibition of pre-replication complex formation Activation of ATR in response to replication stress Assembly of the ORC complex at the origin of replication CDC6 association with the ORC:origin complex CDT1 association with the CDC6:ORC:origin complex Assembly of the pre-replicative complex Orc1 removal from chromatin Activation of the pre-replicative complex G1/S-Specific Transcription		Patella dysplasias, including: Small patella syndrome (SPS); Nail-patella syndrome; Ear-patella-short statute syndrome
Novel	POLDIP2	DNA polymerase delta interacting protein 2
Novel	RNF167	ring finger protein 167
Novel	TADA1	transcriptional adaptor 1	HATs acetylate histones
Novel	TBC1D29P	TBC1 domain family member 29, pseudogene
Novel	UTP4	UTP4 small subunit processome component	rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol		Familial cholestasis, including: Progressive familial intrahepatic cholestasis (PFIC); Benign recurrent intrahepatic cholestasis (BRIC); Intrahepatic cholestasis of pregnancy (ICP); North American Indian childhood cirrhosis (NAIC)
	APP	amyloid beta precursor protein	Platelet degranulation ECM proteoglycans Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) G alpha (q) signalling events G alpha (i) signalling events Lysosome Vesicle Biogenesis Formyl peptide receptors bind formyl peptides and many other ligands TAK1 activates NFkB by phosphorylation and activation of IKKs complex The NLRP3 inflammasome Advanced glycosylation endproduct receptor signaling Advanced glycosylation endproduct receptor signaling Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models Post-translational protein phosphorylation TRAF6 mediated NF-kB activation Insertion of tail-anchored proteins into the endoplasmic reticulum membrane Insertion of tail-anchored proteins into the endoplasmic reticulum membrane Purinergic signaling in leishmaniasis infection Amyloid fiber formation	Deferoxamine Aluminium Zinc L-methionine (R)-S-oxide Resveratrol Tromethamine Phenserine Tetrathiomolybdate CAD106 Mito-4509 Edonerpic Dimercaprol Copper Florbetaben (18F) Florbetapir (18F) Flutemetamol (18F) Zinc acetate Aluminium phosphate Aluminum acetate Zinc chloride Zinc sulfate, unspecified form	Alzheimer's disease (AD)
	AQP12B	aquaporin 12B
	AQP2	aquaporin 2	Vasopressin regulates renal water homeostasis via Aquaporins Passive transport by Aquaporins		Congenital nephrogenic diabetes insipidus (NDI)
	AQP6	aquaporin 6	Passive transport by Aquaporins
	ARL13B	ADP ribosylation factor like GTPase 13B	ARL13B-mediated ciliary trafficking of INPP5E Chaperone Mediated Autophagy Late endosomal microautophagy Aggrephagy Aggrephagy		Joubert syndrome
	ASZ1	ankyrin repeat, SAM and basic leucine zipper domain containing 1	PIWI-interacting RNA (piRNA) biogenesis
	ATP6AP2	ATPase H+ transporting accessory protein 2	Metabolism of Angiotensinogen to Angiotensins Neutrophil degranulation		Syndromic X-linked mental retardation with epilepsy or seizures, including: West syndrome (WS); Partington syndrome (PRTS); Proud syndrome (ACCAG); XMR and epilepsy (XMRE); MRXHF1; XMR OPHN1-related (MRXSO) ; XELBD; XMR, Christianson type (MRXSC); Creatine deficiency syndrome (XL-CDS); Renpenning syndrome (RENS1); Epilepsy and mental retardation limited to females (EFMR); Periventricular nodular heterotopia (PVNH); Hydrocephalus (XLH); XMR, JARID1C related (MRXSJ); Boerjeson-Forssman syndrome (BFLS); CK syndrome (CKS)
	BCL2L13	BCL2 like 13
	BIK	BCL2 interacting killer
	CD53	CD53 molecule	Neutrophil degranulation
	CD74	CD74 molecule	Cell surface interactions at the vascular wall MHC class II antigen presentation

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