Search Results for: TMED5

Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
Novel DCTN1 dynactin subunit 1
  • MHC class II antigen presentation
  • HSP90 chaperone cycle for steroid hormone receptors (SHR)
  • XBP1(S) activates chaperone genes
  • COPI-mediated anterograde transport
  • COPI-independent Golgi-to-ER retrograde traffic
  • Amyotrophic lateral sclerosis (ALS); Lou Gehrig's disease
  • Perry syndrome
  • Distal hereditary motor neuropathies (dHMN)
Novel KIF21B kinesin family member 21B
  • COPI-dependent Golgi-to-ER retrograde traffic
  • Kinesins
Novel PCSK9 proprotein convertase subtilisin/kexin type 9
  • Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
  • VLDLR internalisation and degradation
  • Post-translational protein phosphorylation
  • LDL clearance
  • Alirocumab
  • Inclisiran
  • Hypercholesterolemia, autosomal dominant; Hyperlipoproteinemia, type IIa
Novel TRMT13 tRNA methyltransferase 13 homolog
  • tRNA modification in the nucleus and cytosol
CXCL9 C-X-C motif chemokine ligand 9
  • Chemokine receptors bind chemokines
  • G alpha (i) signalling events
PRMT6 protein arginine methyltransferase 6
  • RMTs methylate histone arginines
  • RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function

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