TARS2 - New-wiki

Novel	Interactant Symbol	Name	Associated Pathways Hide	Binding Drugs Hide
Novel	ANP32E	acidic nuclear phosphoprotein 32 family member E
Novel	CIART	circadian associated repressor of transcription
Novel	GABPB2	GA binding protein transcription factor subunit beta 2
Novel	H3C14	H3 clustered histone 14	Interleukin-7 signaling Interleukin-7 signaling Pre-NOTCH Transcription and Translation Formation of the beta-catenin:TCF transactivating complex PRC2 methylates histones and DNA Condensation of Prophase Chromosomes Oxidative Stress Induced Senescence Senescence-Associated Secretory Phenotype (SASP) HDACs deacetylate histones PKMTs methylate histone lysines HDMs demethylate histones HATs acetylate histones HATs acetylate histones RMTs methylate histone arginines Chromatin modifying enzymes SIRT1 negatively regulates rRNA expression ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression NoRC negatively regulates rRNA expression NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression DNA methylation Transcriptional regulation by small RNAs Activation of anterior HOX genes in hindbrain development during early embryogenesis Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 RNA Polymerase I Promoter Opening RNA Polymerase I Promoter Escape RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function RUNX1 regulates transcription of genes involved in differentiation of HSCs Estrogen-dependent gene expression Meiotic recombination HCMV Early Events HCMV Late Events Transcriptional regulation of granulopoiesis Amyloid fiber formation Factors involved in megakaryocyte development and platelet production
Novel	TNFAIP8L2	TNF alpha induced protein 8 like 2	PI Metabolism
Novel	ZNF687	zinc finger protein 687
	ARL6IP1	ADP ribosylation factor like GTPase 6 interacting protein 1
	ASB6	ankyrin repeat and SOCS box containing 6	Neddylation Antigen processing: Ubiquitination & Proteasome degradation
	FKBP7	FKBP prolyl isomerase 7
	HOMEZ	homeobox and leucine zipper encoding
	PLIN3	perilipin 3	Triglyceride catabolism Retrograde transport at the Trans-Golgi-Network Lipophagy Chaperone Mediated Autophagy Late endosomal microautophagy RHOBTB3 ATPase cycle	Idursulfase Galsulfase
	SLC17A9	solute carrier family 17 member 9
	SYPL1	synaptophysin like 1
	TARS3	threonyl-tRNA synthetase 3
	TNFRSF10D	TNF receptor superfamily member 10d	Cell surface interactions at the vascular wall TP53 Regulates Transcription of Death Receptors and Ligands TRAIL signaling

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