REEP6 - New-wiki

Novel	Interactant Symbol	Name	Associated Pathways Hide	Binding Drugs Hide	Associated Diseases Hide
Novel	ADAT3	adenosine deaminase tRNA specific 3	tRNA modification in the nucleus and cytosol
Novel	IZUMO4	IZUMO family member 4	Acrosome Reaction and Sperm:Oocyte Membrane Binding
Novel	SCAMP4	secretory carrier membrane protein 4
Novel	TMEM259	transmembrane protein 259
Novel	ZNF554	zinc finger protein 554	Generic Transcription Pathway
	ARL6IP1	ADP ribosylation factor like GTPase 6 interacting protein 1
	ATP5PF	ATP synthase peripheral stalk subunit F6	Formation of ATP by chemiosmotic coupling Cristae formation
	CD79A	CD79a molecule	CD22 mediated BCR regulation Antigen activates B Cell Receptor (BCR) leading to generation of second messengers Antigen activates B Cell Receptor (BCR) leading to generation of second messengers		Agammaglobulinemias, including the following six diseases: X-linked agammaglobulinemia (Bruton's agammaglobulinemia, XLA); IgM heavy chain gene deletions; Ig-alpha defect; Autosomal recessive agammaglobulinaemia; B cell-linker protein (BLNK) deficiency; Leucine-rich repeat-containing 8
	CDC37	cell division cycle 37, HSP90 cochaperone	Signaling by ERBB2 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants Constitutive Signaling by EGFRvIII Regulation of necroptotic cell death Downregulation of ERBB2 signaling RHOBTB2 GTPase cycle Constitutive Signaling by Overexpressed ERBB2 Drug-mediated inhibition of ERBB2 signaling Signaling by ERBB2 KD Mutants Resistance of ERBB2 KD mutants to trastuzumab Resistance of ERBB2 KD mutants to sapitinib Resistance of ERBB2 KD mutants to tesevatinib Resistance of ERBB2 KD mutants to neratinib Resistance of ERBB2 KD mutants to osimertinib Resistance of ERBB2 KD mutants to afatinib Resistance of ERBB2 KD mutants to AEE788 Resistance of ERBB2 KD mutants to lapatinib Signaling by ERBB2 ECD mutants Signaling by ERBB2 TMD/JMD mutants Drug resistance in ERBB2 TMD/JMD mutants
	CERT1	ceramide transporter 1
	COQ8A	coenzyme Q8A		Fostamatinib	Coenzyme Q10 deficiency Spinocerebellar ataxia (SCA); Machado-Joseph disease (SCA3)
	CYB561	cytochrome b561
	EBAG9	estrogen receptor binding site associated antigen 9	Estrogen-dependent gene expression
	FHIP1B	FHF complex subunit HOOK interacting protein 1B
	GJA8	gap junction protein alpha 8	Gap junction assembly
	GORASP2	golgi reassembly stacking protein 2	Golgi Cisternae Pericentriolar Stack Reorganization
	GPR152	G protein-coupled receptor 152
	HMBOX1	homeobox containing 1
	HSD17B13	hydroxysteroid 17-beta dehydrogenase 13	Lipid particle organization
	KRTAP3-1	keratin associated protein 3-1	Keratinization

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