POLA2 - New-wiki

Novel	Interactant Symbol	Name	Associated Pathways Hide	Binding Drugs Hide	Associated Diseases Hide
Novel	AGO2	argonaute RISC catalytic component 2	Pre-NOTCH Transcription and Translation MicroRNA (miRNA) biogenesis Ca2+ pathway Small interfering RNA (siRNA) biogenesis Post-transcriptional silencing by small RNAs Transcriptional regulation by small RNAs TP53 Regulates Metabolic Genes MAPK6/MAPK4 signaling Regulation of RUNX1 Expression and Activity Regulation of PTEN mRNA translation Competing endogenous RNAs (ceRNAs) regulate PTEN translation Transcriptional Regulation by MECP2 Transcriptional Regulation by MECP2 Estrogen-dependent gene expression Regulation of MECP2 expression and activity NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux
Novel	ARL2	ADP ribosylation factor like GTPase 2	Post-chaperonin tubulin folding pathway Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane RAS processing	Tagraxofusp
Novel	ATL3	atlastin GTPase 3
Novel	CATSPERZ	catsper channel auxiliary subunit zeta
Novel	KDM2A	lysine demethylase 2A	HDMs demethylate histones
Novel	SAC3D1	SAC3 domain containing 1
Novel	TMEM216	transmembrane protein 216	Anchoring of the basal body to the plasma membrane		Joubert syndrome
Novel	ZNRD2	zinc ribbon domain containing 2
	AKTIP	AKT interacting protein
	APP	amyloid beta precursor protein	Platelet degranulation ECM proteoglycans Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) G alpha (q) signalling events G alpha (i) signalling events Lysosome Vesicle Biogenesis Formyl peptide receptors bind formyl peptides and many other ligands TAK1 activates NFkB by phosphorylation and activation of IKKs complex The NLRP3 inflammasome Advanced glycosylation endproduct receptor signaling Advanced glycosylation endproduct receptor signaling Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models Post-translational protein phosphorylation TRAF6 mediated NF-kB activation Insertion of tail-anchored proteins into the endoplasmic reticulum membrane Insertion of tail-anchored proteins into the endoplasmic reticulum membrane Purinergic signaling in leishmaniasis infection Amyloid fiber formation	Deferoxamine Aluminium Zinc L-methionine (R)-S-oxide Resveratrol Tromethamine Phenserine Tetrathiomolybdate CAD106 Mito-4509 Edonerpic Dimercaprol Copper Florbetaben (18F) Florbetapir (18F) Flutemetamol (18F) Zinc acetate Aluminium phosphate Aluminum acetate Zinc chloride Zinc sulfate, unspecified form	Alzheimer's disease (AD)
	ASCC2	activating signal cointegrator 1 complex subunit 2	ALKBH3 mediated reversal of alkylation damage
	ATP5F1C	ATP synthase F1 subunit gamma	Formation of ATP by chemiosmotic coupling Cristae formation	Quercetin 1-ACETYL-2-CARBOXYPIPERIDINE AUROVERTIN B Piceatannol N1-(2-AMINO-4-METHYLPENTYL)OCTAHYDRO-PYRROLO[1,2-A] PYRIMIDINE
	CPE	carboxypeptidase E	Insulin processing	Insulin human Insulin pork
	CRELD1	cysteine rich with EGF like domains 1			Atrioventricular septal defect; Atrioventricular canal defect
	DCP2	decapping mRNA 2	ATF4 activates genes in response to endoplasmic reticulum stress mRNA decay by 5' to 3' exoribonuclease Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA KSRP (KHSRP) binds and destabilizes mRNA
	DDX24	DEAD-box helicase 24
	DHX34	DExH-box helicase 34
	EIF6	eukaryotic translation initiation factor 6		Copper
	EZH2	enhancer of zeste 2 polycomb repressive complex 2 subunit	PRC2 methylates histones and DNA Oxidative Stress Induced Senescence PKMTs methylate histone lysines Activation of anterior HOX genes in hindbrain development during early embryogenesis Regulation of PTEN gene transcription Regulation of PTEN gene transcription Transcriptional Regulation by E2F6 HCMV Early Events	Tazemetostat CPI-1205
	FAM219A	family with sequence similarity 219 member A

Search Results for: POLA2