Search Results for: PKD2

27 interactions involving PKD2 - polycystin 2, transient receptor potential cation channel found:

Sort by: Symbol Number of Pathways Number of Drugs Number of Diseases
Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
Novel ADH1A alcohol dehydrogenase 1A (class I), alpha polypeptide
  • Abacavir metabolism
  • RA biosynthesis pathway
  • Ethanol oxidation
  • NADH
  • Fomepizole
  • 4-Iodopyrazole
  • N-Cyclopentyl-N-Cyclobutylformamide
Novel ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide
  • RA biosynthesis pathway
  • Ethanol oxidation
  • NADH
  • Fomepizole
  • 2,3,4,5,6-Pentafluorobenzyl Alcohol
  • N-1-methylheptylformamide
  • 2-Ethoxyethanol
  • Cholic Acid
  • 4-Iodopyrazole
  • Pyrazole
  • Para-Bromobenzyl Alcohol
  • 3-Butylthiolane 1-Oxide
  • 5-beta-D-ribofuranosylnicotinamide adenine dinucleotide
  • (R)-N-(1-Methyl-Hexyl)-Formamide
  • Trifluoroethanol
  • Cyclohexylformamide
  • Cpad
  • N-Formylpiperidine
  • 2,3-Difluorobenzyl Alcohol
  • 2,4-Difluorobenzyl Alcohol 2,4-Difluoro-1-(Hydroxymethyl)Benzene
Novel KIF11 kinesin family member 11
  • MHC class II antigen presentation
  • COPI-dependent Golgi-to-ER retrograde traffic
  • Kinesins
  • 3-[(5s)-1-Acetyl-3-(2-Chlorophenyl)-4,5-Dihydro-1h-Pyrazol-5-Yl]Phenol
  • Monastrol
  • Filanesib
  • (4R)-4-(3-HYDROXYPHENYL)-N,N,7,8-TETRAMETHYL-3,4-DIHYDROISOQUINOLINE-2(1H)-CARBOXAMIDE
  • N,N-DIETHYL-2-[(2-THIENYLCARBONYL)AMINO]-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-3-CARBOXAMIDE
  • (5R)-N,N-DIETHYL-5-METHYL-2-[(THIOPHEN-2-YLCARBONYL)AMINO]-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-3-CARBOXAMIDE
  • MK-0731
  • [(4R)-4-(3-HYDROXYPHENYL)-1,6-DIMETHYL-2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDIN-5-YL](PHENYL)METHANONE
  • (2S)-4-(2,5-DIFLUOROPHENYL)-N-METHYL-2-PHENYL-N-PIPERIDIN-4-YL-2,5-DIHYDRO-1H-PYRROLE-1-CARBOXAMIDE
  • (1S)-1-CYCLOPROPYL-2-[(2S)-4-(2,5-DIFLUOROPHENYL)-2-PHENYL-2,5-DIHYDRO-1H-PYRROL-1-YL]-2-OXOETHANAMINE
  • (2S)-4-(2,5-DIFLUOROPHENYL)-N,N-DIMETHYL-2-PHENYL-2,5-DIHYDRO-1H-PYRROLE-1-CARBOXAMIDE
  • (5S)-5-(3-AMINOPROPYL)-3-(2,5-DIFLUOROPHENYL)-N-ETHYL-5-PHENYL-4,5-DIHYDRO-1H-PYRAZOLE-1-CARBOXAMIDE
Novel MTAP methylthioadenosine phosphorylase
  • Methionine salvage pathway
  • Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
  • Adenine
  • (2S,3S,4R,5S)-2-(4-Amino-4,5-dihydro-1H-pyrrolo[3,2-d]pyrimidin-7-yl)-5-[(methylsulfanyl)methyl]-3,4-pyrrolidinediol
  • Formycin
  • 5'-S-methyl-5'-thioadenosine
  • 5'-Deoxy-5'-(Methylthio)-Tubercidin
Novel PPP3CA protein phosphatase 3 catalytic subunit alpha
  • DARPP-32 events
  • Calcineurin activates NFAT
  • Calcineurin activates NFAT
  • FCERI mediated Ca+2 mobilization
  • Ca2+ pathway
  • CLEC7A (Dectin-1) induces NFAT activation
  • Myristic acid
Novel UCHL3 ubiquitin C-terminal hydrolase L3
  • UCH proteinases
  • Synthesis of active ubiquitin: roles of E1 and E2 enzymes
  • Neddylation
ACTN2 actinin alpha 2
  • Platelet degranulation
  • Nephrin family interactions
  • Striated Muscle Contraction
  • Unblocking of NMDA receptors, glutamate binding and activation
  • Unblocking of NMDA receptors, glutamate binding and activation
  • Ras activation upon Ca2+ influx through NMDA receptor
  • RAF/MAP kinase cascade
  • Assembly and cell surface presentation of NMDA receptors
  • Negative regulation of NMDA receptor-mediated neuronal transmission
  • Long-term potentiation
CD2AP CD2 associated protein
  • Nephrin family interactions
  • Nephrotic syndrome and focal segmental glomerulosclerosis
CYSRT1 cysteine rich tail 1
DIAPH1 diaphanous related formin 1
  • RHO GTPases Activate Formins
  • ERBB2 Regulates Cell Motility
  • Neutrophil degranulation
HAX1 HCLS1 associated protein X-1
  • Neutropenic disorders, including the following three diseases: Kostmann syndrome; Cyclic neutropenia; X-linked neutropenia/myelodysplasia
HSF2BP heat shock transcription factor 2 binding protein
KRT40 keratin 40
  • Keratinization
  • Formation of the cornified envelope
KRTAP10-3 keratin associated protein 10-3
  • Keratinization
KRTAP10-8 keratin associated protein 10-8
  • Keratinization
KRTAP6-2 keratin associated protein 6-2
  • Keratinization
LMNA lamin A/C
  • XBP1(S) activates chaperone genes
  • Signaling by BRAF and RAF fusions
  • Restrictive dermopathy
  • Emery-Dreifuss muscular dystrophy
  • Dilated cardiomyopathy (DCM)
  • Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy
  • Mandibuloacral dysplasia
  • Congenital muscular dystrophies (CMD/MDC), including: Merosin-deficient CMD (MDC1A); Ullrich CMD (UCMD); Integrin alpha7-deficient CMD; CMD with joint hyperlaxity (CMDH); CMD with epidermolysis bullosa; Walker-Warburg syndrome (WWS); Muscle-eye-brain disease (MEB); Fukuyama CMD (FCMD); CMD with muscle hypertrophy (MDC1C); CMD with severe intellectual impairment and abnormal glycosylation (MDC1D); Rigid spine syndrome (RSS); LMNA-deficient CMD; CMD with respiratory failure and muscle hypertrophy (MDC1B); Bethlem myopathy
  • Limb-girdle muscular dystrophy (LGMD)
  • Familial partial lipodystrophy (FPL), including the following four diseases: Kobberling-type lipodystrophy (FPLD1); Dunnigan-type lipodystrophy (FPLD2); Dunnigan-like lipodystrophy (FPLD3); AKT2 associated lipodystrophy
  • Hutchinson-Gilford progeria syndrome
MAGEA8 MAGE family member A8
MDFI MyoD family inhibitor
PACS1 phosphofurin acidic cluster sorting protein 1
  • Nef mediated downregulation of MHC class I complex cell surface expression

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