MKKS - New-wiki

Novel	Interactant Symbol	Name	Associated Pathways Hide	Binding Drugs Hide	Associated Diseases Hide
Novel	IL2RB	interleukin 2 receptor subunit beta	RAF/MAP kinase cascade Interleukin-15 signaling Interleukin-15 signaling Interleukin-2 signaling Interleukin receptor SHC signaling	Denileukin diftitox Aldesleukin Basiliximab Daclizumab
Novel	LAMP5	lysosomal associated membrane protein family member 5
Novel	PLCB4	phospholipase C beta 4	PLC beta mediated events PLC beta mediated events Synthesis of IP3 and IP4 in the cytosol G alpha (q) signalling events G alpha (q) signalling events
Novel	PRSS2	serine protease 2	Collagen degradation Alpha-defensins Activation of Matrix Metalloproteinases Neutrophil degranulation Antimicrobial peptides	Monoisopropylphosphorylserine O-Benzylsulfonyl-Serine Benzylamine Benzamidine Phosphorylisopropane Phenethylamine 3-Phenylpropylamine	Hereditary pancreatitis; Hereditary chronic pancreatitis
Novel	SELENOP	selenoprotein P	Platelet degranulation	Zinc Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Novel	TMX4	thioredoxin related transmembrane protein 4
	APP	amyloid beta precursor protein	Platelet degranulation ECM proteoglycans Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) G alpha (q) signalling events G alpha (i) signalling events Lysosome Vesicle Biogenesis Formyl peptide receptors bind formyl peptides and many other ligands TAK1 activates NFkB by phosphorylation and activation of IKKs complex The NLRP3 inflammasome Advanced glycosylation endproduct receptor signaling Advanced glycosylation endproduct receptor signaling Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models Post-translational protein phosphorylation TRAF6 mediated NF-kB activation Insertion of tail-anchored proteins into the endoplasmic reticulum membrane Insertion of tail-anchored proteins into the endoplasmic reticulum membrane Purinergic signaling in leishmaniasis infection Amyloid fiber formation	Deferoxamine Aluminium Zinc L-methionine (R)-S-oxide Resveratrol Tromethamine Phenserine Tetrathiomolybdate CAD106 Mito-4509 Edonerpic Dimercaprol Copper Florbetaben (18F) Florbetapir (18F) Flutemetamol (18F) Zinc acetate Aluminium phosphate Aluminum acetate Zinc chloride Zinc sulfate, unspecified form	Alzheimer's disease (AD)
	CDR2	cerebellar degeneration related protein 2
	PTN	pleiotrophin
	ZBED1	zinc finger BED-type containing 1	SUMOylation of chromatin organization proteins

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