Search Results for: IFT88

Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
Novel ALDH8A1 aldehyde dehydrogenase 8 family member A1
  • RA biosynthesis pathway
Novel MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5
  • Fostamatinib
Novel PCOTH prostate and testis expressed opposite C1QTNF9B and MIPEP
Novel PDX1 pancreatic and duodenal homeobox 1
  • Regulation of gene expression in beta cells
  • Regulation of gene expression in early pancreatic precursor cells
  • Maturity onset diabetes of the young (MODY)
  • Pancreatic agenesis
  • Permanent neonatal diabetes mellitus (PNDM)
Novel SAP18 Sin3A associated protein 18
  • HDACs deacetylate histones
  • NoRC negatively regulates rRNA expression
  • Potential therapeutics for SARS
Novel TRIM24 tripartite motif containing 24
  • Signaling by cytosolic FGFR1 fusion mutants
  • Signaling by FGFR1 in disease
  • Signaling by BRAF and RAF fusions
CAPN7 calpain 7
  • Degradation of the extracellular matrix
CCDC120 coiled-coil domain containing 120
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
  • Protein methylation
EML2 EMAP like 2
FBXO7 F-box protein 7
  • Neddylation
  • Antigen processing: Ubiquitination & Proteasome degradation
  • Parkinson's disease (PD)
ITPKB inositol-trisphosphate 3-kinase B
  • Synthesis of IP3 and IP4 in the cytosol
MSRB1 methionine sulfoxide reductase B1
  • Protein repair
PRRC2A proline rich coiled-coil 2A
RPGR retinitis pigmentosa GTPase regulator
  • Macular degeneration, including: Age-related macular degeneration (ARMD); Patterned dystrophy of retinal pigment epithelium (PDREP); Retinal macular dystrophy 2 (MCDR2); X-linked atrophic macular degeneration (MDXLA)
  • Cone-rod dystrophy and cone dystrophy, including: Cone-rod dystrophy (CORD); Cone dystrophy (COD); Retinal cone dystrophy (RCD)
  • Retinitis pigmentosa (RP)
SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
  • RMTs methylate histone arginines
  • RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
  • Phenethyl Isothiocyanate

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