HOOK1 - New-wiki

Novel	Interactant Symbol	Name	Associated Pathways Hide	Binding Drugs Hide	Associated Diseases Hide
Novel	ERI3	ERI1 exoribonuclease family member 3
Novel	MRPL37	mitochondrial ribosomal protein L37	Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination
Novel	MYSM1	Myb like, SWIRM and MPN domains 1	Metalloprotease DUBs
Novel	S100A7	S100 calcium binding protein A7	Neutrophil degranulation Metal sequestration by antimicrobial proteins	Ibuprofen Zinc 8-anilinonaphthalene-1-sulfonic acid Dexibuprofen Zinc acetate Zinc chloride Zinc sulfate, unspecified form
	AKTIP	AKT interacting protein
	ANK3	ankyrin 3	Interaction between L1 and Ankyrins Interaction between L1 and Ankyrins COPI-mediated anterograde transport
	ANKRD23	ankyrin repeat domain 23
	CDC5L	cell division cycle 5 like	mRNA Splicing - Major Pathway
	CDK4	cyclin dependent kinase 4	SCF(Skp2)-mediated degradation of p27/p21 Oxidative Stress Induced Senescence Senescence-Associated Secretory Phenotype (SASP) Oncogene Induced Senescence RMTs methylate histone arginines Transcriptional regulation of white adipocyte differentiation Cyclin D associated events in G1 Ubiquitin-dependent degradation of Cyclin D Ubiquitin-dependent degradation of Cyclin D PTK6 Regulates Cell Cycle Transcriptional regulation by RUNX2 Meiotic recombination Transcriptional regulation of granulopoiesis Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 Defective binding of RB1 mutants to E2F1,(E2F2, E2F3)	Purvalanol Alvocidib Palbociclib Ribociclib Abemaciclib Fostamatinib	Glioma Malignant melanoma Cervical cancer
	CWF19L2	CWF19 like cell cycle control factor 2
	FAM161A	FAM161 centrosomal protein A			Retinitis pigmentosa (RP)
	FHIP1B	FHF complex subunit HOOK interacting protein 1B
	HOOK2	hook microtubule tethering protein 2
	HOOK3	hook microtubule tethering protein 3
	LMO2	LIM domain only 2	RUNX1 regulates transcription of genes involved in differentiation of HSCs		Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia)
	MEOX2	mesenchyme homeobox 2
	PIAS2	protein inhibitor of activated STAT 2	Activation of anterior HOX genes in hindbrain development during early embryogenesis
	SYCE1	synaptonemal complex central element protein 1	Meiotic synapsis
	TBC1D7	TBC1 domain family member 7	TBC/RABGAPs
	TFIP11	tuftelin interacting protein 11	mRNA Splicing - Major Pathway

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