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Novel |
CD9 |
CD9 molecule |
- Platelet degranulation
- Acrosome Reaction and Sperm:Oocyte Membrane Binding
- Uptake and function of diphtheria toxin
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Novel |
RAD51AP1 |
RAD51 associated protein 1 |
- HDR through Homologous Recombination (HRR)
- Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)
- Resolution of D-loop Structures through Holliday Junction Intermediates
- Homologous DNA Pairing and Strand Exchange
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Novel |
XRCC5 |
X-ray repair cross complementing 5 |
- 2-LTR circle formation
- Cytosolic sensors of pathogen-associated DNA
- IRF3-mediated induction of type I IFN
- Nonhomologous End-Joining (NHEJ)
- Neutrophil degranulation
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CABP1 |
calcium binding protein 1 |
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CACNB3 |
calcium voltage-gated channel auxiliary subunit beta 3 |
- Presynaptic depolarization and calcium channel opening
- Adrenaline,noradrenaline inhibits insulin secretion
- NCAM1 interactions
- Regulation of insulin secretion
- Regulation of insulin secretion
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- Ergocalciferol
- Enflurane
- Ranolazine
- Phenytoin
- Topiramate
- Nimodipine
- Spironolactone
- Magnesium sulfate
- Levomenthol
- Miconazole
- Amiodarone
- Mibefradil
- Dronedarone
- Trimebutine
- Benidipine
- Cilnidipine
- Lacidipine
- Manidipine
- Butamben
- Bioallethrin
- Bioallethrin
- Fish oil
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COPS5 |
COP9 signalosome subunit 5 |
- DNA Damage Recognition in GG-NER
- Formation of TC-NER Pre-Incision Complex
- Cargo recognition for clathrin-mediated endocytosis
- Neddylation
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GNB1 |
G protein subunit beta 1 |
- Activation of G protein gated Potassium channels
- Glucagon signaling in metabolic regulation
- G-protein activation
- Activation of the phototransduction cascade
- Activation of the phototransduction cascade
- Inactivation, recovery and regulation of the phototransduction cascade
- Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
- Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
- Olfactory Signaling Pathway
- ADP signalling through P2Y purinoceptor 12
- G beta:gamma signalling through PI3Kgamma
- Prostacyclin signalling through prostacyclin receptor
- Prostacyclin signalling through prostacyclin receptor
- Adrenaline,noradrenaline inhibits insulin secretion
- Adrenaline,noradrenaline inhibits insulin secretion
- Ca2+ pathway
- Ca2+ pathway
- G alpha (q) signalling events
- G alpha (12/13) signalling events
- G beta:gamma signalling through PLC beta
- G alpha (s) signalling events
- ADP signalling through P2Y purinoceptor 1
- ADP signalling through P2Y purinoceptor 1
- G alpha (i) signalling events
- G alpha (z) signalling events
- Glucagon-type ligand receptors
- Thromboxane signalling through TP receptor
- Vasopressin regulates renal water homeostasis via Aquaporins
- Thrombin signalling through proteinase activated receptors (PARs)
- Thrombin signalling through proteinase activated receptors (PARs)
- Presynaptic function of Kainate receptors
- Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
- G beta:gamma signalling through BTK
- G beta:gamma signalling through CDC42
- Extra-nuclear estrogen signaling
- ADORA2B mediated anti-inflammatory cytokines production
- Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
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HDAC4 |
histone deacetylase 4 |
- NOTCH1 Intracellular Domain Regulates Transcription
- Constitutive Signaling by NOTCH1 PEST Domain Mutants
- Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
- Notch-HLH transcription pathway
- SUMOylation of intracellular receptors
- SUMOylation of chromatin organization proteins
- RUNX2 regulates chondrocyte maturation
- RUNX3 regulates p14-ARF
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- Zinc
- Belinostat
- Romidepsin
- Panobinostat
- N-hydroxy-5-[(3-phenyl-5,6-dihydroimidazo[1,2-a]pyrazin-7(8H)-yl)carbonyl]thiophene-2-carboxamide
- 2,2,2-TRIFLUORO-1-{5-[(3-PHENYL-5,6-DIHYDROIMIDAZO[1,2-A]PYRAZIN-7(8H)-YL)CARBONYL]THIOPHEN-2-YL}ETHANE-1,1-DIOL
- Zinc acetate
- Zinc chloride
- Zinc sulfate, unspecified form
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- Brachydacytly-mental retardation syndrome and Smith-Magenis syndrome
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PCBD1 |
pterin-4 alpha-carbinolamine dehydratase 1 |
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- L-erythro-7,8-dihydrobiopterin
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- Phenylketonuria (PKU); Hyperphenylalaninemia, BH4-deficient
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PPM1A |
protein phosphatase, Mg2+/Mn2+ dependent 1A |
- Downregulation of SMAD2/3:SMAD4 transcriptional activity
- Energy dependent regulation of mTOR by LKB1-AMPK
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PRKACA |
protein kinase cAMP-activated catalytic subunit alpha |
- PKA-mediated phosphorylation of CREB
- PKA-mediated phosphorylation of key metabolic factors
- Triglyceride catabolism
- PKA activation
- PKA activation in glucagon signalling
- DARPP-32 events
- Regulation of PLK1 Activity at G2/M Transition
- Loss of Nlp from mitotic centrosomes
- Recruitment of mitotic centrosome proteins and complexes
- Loss of proteins required for interphase microtubule organization from the centrosome
- Recruitment of NuMA to mitotic centrosomes
- Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
- Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
- Rap1 signalling
- Regulation of insulin secretion
- Vasopressin regulates renal water homeostasis via Aquaporins
- VEGFA-VEGFR2 Pathway
- CREB1 phosphorylation through the activation of Adenylate Cyclase
- CREB1 phosphorylation through the activation of Adenylate Cyclase
- Interleukin-3, Interleukin-5 and GM-CSF signaling
- Ion homeostasis
- Degradation of GLI1 by the proteasome
- Degradation of GLI2 by the proteasome
- GLI3 is processed to GLI3R by the proteasome
- Hedgehog 'off' state
- Anchoring of the basal body to the plasma membrane
- CD209 (DC-SIGN) signaling
- MAPK6/MAPK4 signaling
- RET signaling
- AURKA Activation by TPX2
- HDL assembly
- ROBO receptors bind AKAP5
- Loss of phosphorylation of MECP2 at T308
- Regulation of MECP2 expression and activity
- Regulation of glycolysis by fructose 2,6-bisphosphate metabolism
- ADORA2B mediated anti-inflammatory cytokines production
- ADORA2B mediated anti-inflammatory cytokines production
- FCGR3A-mediated IL10 synthesis
- FCGR3A-mediated IL10 synthesis
- Factors involved in megakaryocyte development and platelet production
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- Pentanal
- Balanol Analog 2
- 3-[(3-sec-butyl-4-hydroxybenzoyl)amino]azepan-4-yl 4-(2-hydroxy-5-methoxybenzoyl)benzoate
- Phosphonothreonine
- Balanol Analog 1
- 3,5-Diiodotyrosine
- Balanol
- Dexfosfoserine
- S,S-(2-Hydroxyethyl)Thiocysteine
- Hydroxyfasudil
- (2S)-1-(3H-Indol-3-yl)-3-{[5-(6-isoquinolinyl)-3-pyridinyl]oxy}-2-propanamine
- (2S)-1-{[5-(1H-Indazol-5-yl)-3-pyridinyl]oxy}-3-(7aH-indol-3-yl)-2-propanamine
- (1S)-2-(1H-INDOL-3-YL)-1-[({5-[(E)-2-PYRIDIN-4-YLVINYL]PYRIDIN-3-YL}OXY)METHYL]ETHYLAMINE
- (2S)-1-(6H-INDOL-3-YL)-3-{[5-(7H-PYRAZOLO[3,4-C]PYRIDIN-5-YL)PYRIDIN-3-YL]OXY}PROPAN-2-AMINE
- (1S)-1-(1H-INDOL-3-YLMETHYL)-2-(2-PYRIDIN-4-YL-[1,7]NAPHTYRIDIN-5-YLOXY)-EHYLAMINE
- N-[(1S)-2-AMINO-1-(2,4-DICHLOROBENZYL)ETHYL]-5-[2-(METHYLAMINO)PYRIMIDIN-4-YL]THIOPHENE-2-CARBOXAMIDE
- 3-(1H-indol-3-yl)-4-{1-[2-(1-methylpyrrolidin-2-yl)ethyl]-1H-indol-3-yl}-1H-pyrrole-2,5-dione
- (4R,2S)-5'-(4-(4-CHLOROBENZYLOXY)PYRROLIDIN-2-YLMETHANESULFONYL)ISOQUINOLINE
- N-METHYL-1-[4-(9H-PURIN-6-YL)PHENYL]METHANAMINE
- (S)-1-PHENYL-1-[4-(9H-PURIN-6-YL)PHENYL]METHANAMINE
- 6-{4-[4-(4-CHLOROPHENYL)PIPERIDIN-4-YL]PHENYL}-9H-PURINE
- (2R)-2-(4-chlorophenyl)-2-[4-(1H-pyrazol-4-yl)phenyl]ethanamine
- (2S)-2-(4-chlorophenyl)-2-[4-(1H-pyrazol-4-yl)phenyl]ethanamine
- 4-(4-CHLOROPHENYL)-4-[4-(1H-PYRAZOL-4-YL)PHENYL]PIPERIDINE
- (2R)-2-(4-CHLOROPHENYL)-2-PHENYLETHANAMINE
- (S)-2-METHYL-1-[(4-METHYL-5-ISOQUINOLINE)SULFONYL]-HOMOPIPERAZINE
- ISOQUINOLINE-5-SULFONIC ACID (2-(2-(4-CHLOROBENZYLOXY)ETHYLAMINO)ETHYL)AMIDE
- H-89
- 5-(2-methylpiperazine-1-sulfonyl)isoquinoline
- N-[2-(METHYLAMINO)ETHYL]-5-ISOQUINOLINESULFONAMIDE
- 2-[4-(3-METHYL-1H-PYRAZOL-4-YL)PHENYL]ETHANAMINE
- (2S)-1-(1H-INDOL-3-YL)-3-{[5-(3-METHYL-1H-INDAZOL-5-YL)PYRIDIN-3-YL]OXY}PROPAN-2-AMINE
- 3-pyridin-4-yl-1H-indazole
- 5-benzyl-1,3-thiazol-2-amine
- 1-[4-(4-chlorophenyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-4-yl]methanamine
- 1-[4-(4-chlorobenzyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-4-yl]methanamine
- 4-(4-chlorobenzyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-4-aminium
- Fasudil
- Myristic acid
- A-674563
- 3-PYRIDIN-4-YL-2,4-DIHYDRO-INDENO[1,2-.C.] PYRAZOLE
- Y-27632
- Ellagic acid
- Fostamatinib
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RIMS1 |
regulating synaptic membrane exocytosis 1 |
- Serotonin Neurotransmitter Release Cycle
- Norepinephrine Neurotransmitter Release Cycle
- Glutamate Neurotransmitter Release Cycle
- Dopamine Neurotransmitter Release Cycle
- Acetylcholine Neurotransmitter Release Cycle
- GABA synthesis, release, reuptake and degradation
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- Cone-rod dystrophy and cone dystrophy, including: Cone-rod dystrophy (CORD); Cone dystrophy (COD); Retinal cone dystrophy (RCD)
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RYR2 |
ryanodine receptor 2 |
- Stimuli-sensing channels
- Ion homeostasis
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- Arrhythmogenic right ventricular cardiomyopathy (ARVC)
- Catecholaminergic polymorphic ventricular tachycardia
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SRI |
sorcin |
- Stimuli-sensing channels
- Reduction of cytosolic Ca++ levels
- Sodium/Calcium exchangers
- Ion homeostasis
- Ion transport by P-type ATPases
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- Calcium citrate
- Calcium Phosphate
- Calcium phosphate dihydrate
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