ANKS6 - New-wiki

Novel	Interactant Symbol	Name	Associated Pathways Hide	Binding Drugs Hide	Associated Diseases Hide
Novel	MFSD14C	major facilitator superfamily domain containing 14C
	AGTRAP	angiotensin II receptor associated protein	Signaling by BRAF and RAF fusions
	APP	amyloid beta precursor protein	Platelet degranulation ECM proteoglycans Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) G alpha (q) signalling events G alpha (i) signalling events Lysosome Vesicle Biogenesis Formyl peptide receptors bind formyl peptides and many other ligands TAK1 activates NFkB by phosphorylation and activation of IKKs complex The NLRP3 inflammasome Advanced glycosylation endproduct receptor signaling Advanced glycosylation endproduct receptor signaling Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models Post-translational protein phosphorylation TRAF6 mediated NF-kB activation Insertion of tail-anchored proteins into the endoplasmic reticulum membrane Insertion of tail-anchored proteins into the endoplasmic reticulum membrane Purinergic signaling in leishmaniasis infection Amyloid fiber formation	Deferoxamine Aluminium Zinc L-methionine (R)-S-oxide Resveratrol Tromethamine Phenserine Tetrathiomolybdate CAD106 Mito-4509 Edonerpic Dimercaprol Copper Florbetaben (18F) Florbetapir (18F) Flutemetamol (18F) Zinc acetate Aluminium phosphate Aluminum acetate Zinc chloride Zinc sulfate, unspecified form	Alzheimer's disease (AD)
	BCL2L2	BCL2 like 2		Navitoclax
	BET1	Bet1 golgi vesicular membrane trafficking protein	COPII-mediated vesicle transport COPI-mediated anterograde transport
	C1GALT1	core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1	Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS) O-linked glycosylation of mucins
	C5	complement C5	Terminal pathway of complement Activation of C3 and C5 Peptide ligand-binding receptors G alpha (i) signalling events Regulation of Complement cascade	Human immunoglobulin G Eculizumab Zinc Copper Ravulizumab Zinc acetate Zinc chloride Zinc sulfate, unspecified form	Late complement pathway defects, including the following seven diseases: C5 deficiency; C6 deficiency; C7 deficiency; C8 alpha-chain deficiency; C8 beta-chain deficiency; C8 gamma-chain deficiency; C9 deficiency
	EMD	emerin	Nuclear Envelope Breakdown Initiation of Nuclear Envelope (NE) Reformation Depolymerisation of the Nuclear Lamina Insertion of tail-anchored proteins into the endoplasmic reticulum membrane Insertion of tail-anchored proteins into the endoplasmic reticulum membrane		Emery-Dreifuss muscular dystrophy
	EMP1	epithelial membrane protein 1
	IGFBP5	insulin like growth factor binding protein 5	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
	MARCHF5	membrane associated ring-CH-type finger 5
	PITPNC1	phosphatidylinositol transfer protein cytoplasmic 1
	RTP2	receptor transporter protein 2	Olfactory Signaling Pathway
	SMIM1	small integral membrane protein 1 (Vel blood group)
	STRIT1	small transmembrane regulator of ion transport 1
	STX7	syntaxin 7
	TMEM120B	transmembrane protein 120B
	TMEM60	transmembrane protein 60
	VAMP4	vesicle associated membrane protein 4	Retrograde transport at the Trans-Golgi-Network Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
	VEZT	vezatin, adherens junctions transmembrane protein

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