Search Results for: ALG8

Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
Novel IQGAP2 IQ motif containing GTPase activating protein 2
  • RHO GTPases activate IQGAPs
  • Neutrophil degranulation
Novel NARS2 asparaginyl-tRNA synthetase 2, mitochondrial
  • Mitochondrial tRNA aminoacylation
  • Asparagine
Novel RSF1 remodeling and spacing factor 1
  • Deposition of new CENPA-containing nucleosomes at the centromere
Novel TMEM126B transmembrane protein 126B
  • Complex I biogenesis
BIK BCL2 interacting killer
CLRN1 clarin 1
  • Usher syndrome (US)
CREB3 cAMP responsive element binding protein 3
  • CREB3 factors activate genes
  • CREB3 factors activate genes
CREB3L1 cAMP responsive element binding protein 3 like 1
  • CREB3 factors activate genes
CYB5R3 cytochrome b5 reductase 3
  • Vitamin C (ascorbate) metabolism
  • Phase I - Functionalization of compounds
  • Neutrophil degranulation
  • NADH
  • Flavin adenine dinucleotide
  • Copper
  • Methemoglobinemia
FAM209A family with sequence similarity 209 member A
GPX8 glutathione peroxidase 8 (putative)
  • Detoxification of Reactive Oxygen Species
  • Glutathione
  • Glutathione disulfide
LMNA lamin A/C
  • XBP1(S) activates chaperone genes
  • Signaling by BRAF and RAF fusions
  • Restrictive dermopathy
  • Emery-Dreifuss muscular dystrophy
  • Dilated cardiomyopathy (DCM)
  • Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy
  • Mandibuloacral dysplasia
  • Congenital muscular dystrophies (CMD/MDC), including: Merosin-deficient CMD (MDC1A); Ullrich CMD (UCMD); Integrin alpha7-deficient CMD; CMD with joint hyperlaxity (CMDH); CMD with epidermolysis bullosa; Walker-Warburg syndrome (WWS); Muscle-eye-brain disease (MEB); Fukuyama CMD (FCMD); CMD with muscle hypertrophy (MDC1C); CMD with severe intellectual impairment and abnormal glycosylation (MDC1D); Rigid spine syndrome (RSS); LMNA-deficient CMD; CMD with respiratory failure and muscle hypertrophy (MDC1B); Bethlem myopathy
  • Limb-girdle muscular dystrophy (LGMD)
  • Familial partial lipodystrophy (FPL), including the following four diseases: Kobberling-type lipodystrophy (FPLD1); Dunnigan-type lipodystrophy (FPLD2); Dunnigan-like lipodystrophy (FPLD3); AKT2 associated lipodystrophy
  • Hutchinson-Gilford progeria syndrome
MFSD6 major facilitator superfamily domain containing 6
NAE1 NEDD8 activating enzyme E1 subunit 1
  • Neddylation
  • ATP
RPS6KA5 ribosomal protein S6 kinase A5
  • ERK/MAPK targets
  • CREB phosphorylation
  • NCAM signaling for neurite out-growth
  • Recycling pathway of L1
  • CD209 (DC-SIGN) signaling
SAR1A secretion associated Ras related GTPase 1A

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