CSNK2B - New-wiki

Interactant Symbol	Name	Associated Pathways Hide	Binding Drugs Hide	Associated Diseases Hide
MDM2	MDM2 proto-oncogene	AKT phosphorylates targets in the cytosol Oxidative Stress Induced Senescence Oncogene Induced Senescence SUMOylation of transcription factors SUMOylation of ubiquitinylation proteins Trafficking of AMPA receptors Constitutive Signaling by AKT1 E17K in Cancer Ub-specific processing proteases Regulation of TP53 Activity through Phosphorylation Regulation of TP53 Degradation Regulation of TP53 Activity through Methylation Stabilization of p53 Regulation of RUNX3 expression and activity	Zinc Cis-[4,5-Bis-(4-Bromophenyl)-2-(2-Ethoxy-4-Methoxyphenyl)-4,5-Dihydroimidazol-1-Yl]-[4-(2-Hydroxyethyl)Piperazin-1-Yl]Methanone Cis-[4,5-Bis-(4-Chlorophenyl)-2-(2-Isopropoxy-4-Methoxyphenyl)-4,5-Dihyd Roimidazol-1-Yl]-Piperazin-1-Yl-Methanone Zinc acetate Zinc chloride Zinc sulfate, unspecified form	Choriocarcinoma Osteosarcoma Glioma Penile cancer Alveolar rhabdomyosarcoma
MME	membrane metalloendopeptidase	Metabolism of Angiotensinogen to Angiotensins Neutrophil degranulation	Candoxatril Omapatrilat N-[3-[(1-Aminoethyl)(Hydroxy)Phosphoryl]-2-(1,1'-Biphenyl-4-Ylmethyl)Propanoyl]Alanine Phosphoramidon N-(3-Phenyl-2-Sulfanylpropanoyl)Phenylalanylalanine [2(R,S)-2-Sulfanylheptanoyl]-Phe-Ala Daglutril 2-[(1S)-1-BENZYL-2-SULFANYLETHYL]-1H-IMIDAZO[4,5-C]PYRIDIN-5-IUM Thiorphan Sacubitril Candoxatrilat
MOXD1	monooxygenase DBH like 1
MPP2	membrane palmitoylated protein 2
NAP1L1	nucleosome assembly protein 1 like 1
NCF1	neutrophil cytosolic factor 1	ROS and RNS production in phagocytes Cross-presentation of particulate exogenous antigens (phagosomes) Detoxification of Reactive Oxygen Species VEGFA-VEGFR2 Pathway RHO GTPases Activate NADPH Oxidases	Dextromethorphan	Chronic granulomatous disease, including the following four diseases: X-linked CGD (gp91 phox CGD); p22phox deficiency (p22phox CGD); p47phox deficiency (p47phox CGD); p67phox deficiency (p67phox CGD)
NGDN	neuroguidin
NMT2	N-myristoyltransferase 2	Membrane binding and targetting of GAG proteins Inactivation, recovery and regulation of the phototransduction cascade	Myristoyl-Coa S-(2-oxo)pentadecylcoa 1-(CYCLOHEXYLAMINO)-3-(6-METHYL-3,4-DIHYDRO-1H-CARBAZOL-9(2H)-YL)PROPAN-2-OL (Z)-3-BENZYL-5-(2-HYDROXY-3-NITROBENZYLIDENE)-2-THIOXOTHIAZOLIDIN-4-ONE
NOLC1	nucleolar and coiled-body phosphoprotein 1		Doxorubicin
NOTCH3	notch receptor 3	Pre-NOTCH Processing in the Endoplasmic Reticulum Pre-NOTCH Transcription and Translation Pre-NOTCH Processing in Golgi Pre-NOTCH Processing in Golgi Notch-HLH transcription pathway Defective LFNG causes SCDO3 NOTCH3 Activation and Transmission of Signal to the Nucleus NOTCH3 Activation and Transmission of Signal to the Nucleus NOTCH3 Intracellular Domain Regulates Transcription NOTCH3 Intracellular Domain Regulates Transcription Noncanonical activation of NOTCH3		Cerebral autosomal dominant arteriopathy with subcortical infarcts and leucoencephalopathy (CADASIL)
NPAS2	neuronal PAS domain protein 2	BMAL1:CLOCK,NPAS2 activates circadian gene expression BMAL1:CLOCK,NPAS2 activates circadian gene expression PPARA activates gene expression Circadian Clock
NRBP1	nuclear receptor binding protein 1	Nuclear Receptor transcription pathway
NRF1	nuclear respiratory factor 1	PPARA activates gene expression Transcriptional activation of mitochondrial biogenesis Transcriptional activation of mitochondrial biogenesis
NTAQ1	N-terminal glutamine amidase 1
ODC1	ornithine decarboxylase 1	Regulation of ornithine decarboxylase (ODC) Metabolism of polyamines	Pyridoxal phosphate Spermine Putrescine Pyridoxine phosphate N-Pyridoxyl-Glycine-5-Monophosphate L-Eflornithine N(6)-(pyridoxal phosphate)-L-lysine Geneticin Eflornithine
OGA	O-GlcNAcase		Streptozocin
OGT	O-linked N-acetylglucosamine (GlcNAc) transferase	HATs acetylate histones RIPK1-mediated regulated necrosis Regulation of necroptotic cell death UCH proteinases
PDS5A	PDS5 cohesin associated factor A	Separation of Sister Chromatids Establishment of Sister Chromatid Cohesion Cohesin Loading onto Chromatin Resolution of Sister Chromatid Cohesion
PER1	period circadian regulator 1	Circadian Clock
PER2	period circadian regulator 2	Circadian Clock		Familial advanced sleep phase syndrome

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