Search Results for: UPF1

109 interactions involving UPF1 - UPF1 RNA helicase and ATPase found:

Sort by: Symbol Number of Pathways Number of Drugs Number of Diseases
Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
RPRD2 regulation of nuclear pre-mRNA domain containing 2
  • RNA polymerase II transcribes snRNA genes
  • RNA polymerase II transcribes snRNA genes
SMG1 SMG1 nonsense mediated mRNA decay associated PI3K related kinase
  • Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
SMG5 SMG5 nonsense mediated mRNA decay factor
  • Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
STAU1 staufen double-stranded RNA binding protein 1
SUMO2 small ubiquitin like modifier 2
  • Vitamin D (calciferol) metabolism
  • SUMO is conjugated to E1 (UBA2:SAE1)
  • SUMO is transferred from E1 to E2 (UBE2I, UBC9)
  • SUMO is proteolytically processed
  • SUMOylation of DNA damage response and repair proteins
  • SUMOylation of transcription factors
  • SUMOylation of transcription cofactors
  • SUMOylation of SUMOylation proteins
  • SUMOylation of intracellular receptors
  • SUMOylation of intracellular receptors
  • SUMOylation of chromatin organization proteins
  • SUMOylation of RNA binding proteins
  • SUMOylation of DNA replication proteins
  • Processing of DNA double-strand break ends
  • Formation of Incision Complex in GG-NER
UPF2 UPF2 regulator of nonsense mediated mRNA decay
  • Regulation of expression of SLITs and ROBOs
  • Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
UPF3A UPF3A regulator of nonsense mediated mRNA decay
  • Regulation of expression of SLITs and ROBOs
  • Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
UPF3B UPF3B regulator of nonsense mediated mRNA decay
  • Transport of Mature mRNA derived from an Intron-Containing Transcript
  • mRNA Splicing - Major Pathway
  • mRNA 3'-end processing
  • RNA Polymerase II Transcription Termination
  • Regulation of expression of SLITs and ROBOs
  • Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
  • Syndromic X-linked mental retardation, including: Turner type (MRXST); Siderius type (MRXSSD) ; Cabezas type (MRXC); Raymond type (MRXSR); Type10 (MRXS10); Type14 (MRXS14); Mental retardation with isolated growth hormone deficiency (MRGH)
XRN1 5'-3' exoribonuclease 1
  • mRNA decay by 5' to 3' exoribonuclease
  • Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA
  • Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA

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