Search Results for: SRPK2

Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
DNAJC8 DnaJ heat shock protein family (Hsp40) member C8
  • mRNA Splicing - Major Pathway
DOCK3 dedicator of cytokinesis 3
  • NTRK2 activates RAC1
  • NTRK2 activates RAC1
  • Factors involved in megakaryocyte development and platelet production
DRAP1 DR1 associated protein 1
  • Signaling by NODAL
  • Signaling by Activin
DRG1 developmentally regulated GTP binding protein 1
ECT2 epithelial cell transforming 2
  • NRAGE signals death through JNK
  • Rho GTPase cycle
  • G alpha (12/13) signalling events
EED embryonic ectoderm development
  • PRC2 methylates histones and DNA
  • Oxidative Stress Induced Senescence
  • PKMTs methylate histone lysines
  • Activation of anterior HOX genes in hindbrain development during early embryogenesis
  • Regulation of PTEN gene transcription
  • Regulation of PTEN gene transcription
  • Transcriptional Regulation by E2F6
  • HCMV Early Events
EFCAB12 EF-hand calcium binding domain 12
EGLN2 egl-9 family hypoxia inducible factor 2
  • Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
  • Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
  • Ascorbic acid
  • Roxadustat
EIF1AY eukaryotic translation initiation factor 1A Y-linked
EIF3A eukaryotic translation initiation factor 3 subunit A
  • L13a-mediated translational silencing of Ceruloplasmin expression
  • Translation initiation complex formation
  • Formation of a pool of free 40S subunits
  • Formation of the ternary complex, and subsequently, the 43S complex
  • Ribosomal scanning and start codon recognition
  • GTP hydrolysis and joining of the 60S ribosomal subunit
EIF4B eukaryotic translation initiation factor 4B
  • L13a-mediated translational silencing of Ceruloplasmin expression
  • mTORC1-mediated signalling
  • Deadenylation of mRNA
  • Translation initiation complex formation
  • Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
  • Ribosomal scanning and start codon recognition
  • GTP hydrolysis and joining of the 60S ribosomal subunit
EIF4G1 eukaryotic translation initiation factor 4 gamma 1
  • ISG15 antiviral mechanism
  • L13a-mediated translational silencing of Ceruloplasmin expression
  • mTORC1-mediated signalling
  • Deadenylation of mRNA
  • AUF1 (hnRNP D0) binds and destabilizes mRNA
  • Translation initiation complex formation
  • Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
  • Ribosomal scanning and start codon recognition
  • GTP hydrolysis and joining of the 60S ribosomal subunit
  • Regulation of expression of SLITs and ROBOs
  • Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
  • Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
ELAVL3 ELAV like RNA binding protein 3
ELP6 elongator acetyltransferase complex subunit 6
  • HATs acetylate histones
ENOX2 ecto-NOX disulfide-thiol exchanger 2
  • Idronoxil
ENSA endosulfine alpha
  • MASTL Facilitates Mitotic Progression
  • MASTL Facilitates Mitotic Progression
EPB41L1 erythrocyte membrane protein band 4.1 like 1
  • Trafficking of AMPA receptors
  • Neurexins and neuroligins
EPB41L4A erythrocyte membrane protein band 4.1 like 4A
EPB41L4B erythrocyte membrane protein band 4.1 like 4B
EPM2A EPM2A glucan phosphatase, laforin
  • Glycogen synthesis
  • Myoclonic epilepsy of Lafora
  • Progressive myoclonic epilepsy (PME), including: Lafora disease (LBD); Unverricht-Lundborg disease (ULD); Neuronal ceroid lipofuscinoses (NCL); Type I sialidosis; Action myoclonus-renal failure syndrome (AMRF); Type III Gaucher disease (GD)

Page 6 out of 22 pages