Search Results for: PRKACA

Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
DRD1 dopamine receptor D1
  • Dopamine receptors
  • G alpha (s) signalling events
  • ADORA2B mediated anti-inflammatory cytokines production
  • Ziprasidone
  • Cabergoline
  • Cabergoline
  • Olanzapine
  • Olanzapine
  • Methylergometrine
  • Clozapine
  • Phenylpropanolamine
  • Loxapine
  • Loxapine
  • Imipramine
  • Chlorpromazine
  • Chlorpromazine
  • Haloperidol
  • Triflupromazine
  • Amoxapine
  • Lamotrigine
  • Cinnarizine
  • Lisuride
  • Fluphenazine
  • Thioridazine
  • Ergotamine
  • Apomorphine
  • Paroxetine
  • Trimipramine
  • Risperidone
  • Fenoldopam
  • Minaprine
  • Perphenazine
  • Flupentixol
  • Dopamine
  • Dopamine
  • Carphenazine
  • Ergoloid mesylate
  • Pergolide
  • Bromocriptine
  • Quetiapine
  • Levodopa
  • Aripiprazole
  • Chlorprothixene
  • Paliperidone
  • Methotrimeprazine
  • Periciazine
  • Acepromazine
  • Pipotiazine
  • Thioproperazine
  • Thiothixene
  • Zuclopenthixol
  • Iloperidone
  • Rotigotine
  • Lumateperone
  • Mianserin
  • Asenapine
  • Quinagolide
  • Zotepine
  • Pipamperone
  • Dihydro-alpha-ergocryptine
  • Epicriptine
  • Pipradrol
  • Tetrahydropalmatine
  • Dihydrexidine
  • Dihydroergocristine
  • Aripiprazole lauroxil
DSP desmoplakin
  • Apoptotic cleavage of cell adhesion proteins
  • Neutrophil degranulation
  • Keratinization
  • Formation of the cornified envelope
  • Zinc
  • Artenimol
  • Zinc acetate
  • Arrhythmogenic right ventricular cardiomyopathy (ARVC)
  • Naxos disease and Carvajal syndrome
  • Striate palmoplantar keratoderma
  • Skin fragility-woolly hair syndrome
  • Epidermolysis bullosa simplex, including: Epidermolysis bullosa simplex, Dowling-Meara type (EBS-DM); Epidermolysis bullosa simplex, Koebner type (EBS-K); Epidermolysis bullosa simplex, Weber-Cockayne type (EBS-WC); Epidermolysis bullosa simplex with mottled pigmentation (EBS-MP); Epidermolysis bullosa simplex with migratory circinate erythema; Epidermolysis bullosa simplex, recessive; Epidermolysis bullosa, lethal acantholytic
EEF2K eukaryotic elongation factor 2 kinase
  • mTORC1-mediated signalling
EGFR epidermal growth factor receptor
  • Signaling by ERBB2
  • Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants
  • Signaling by ERBB4
  • SHC1 events in ERBB2 signaling
  • SHC1 events in ERBB2 signaling
  • PLCG1 events in ERBB2 signaling
  • PIP3 activates AKT signaling
  • Signaling by EGFR
  • GRB2 events in EGFR signaling
  • GAB1 signalosome
  • SHC1 events in EGFR signaling
  • EGFR downregulation
  • GRB2 events in ERBB2 signaling
  • PI3K events in ERBB2 signaling
  • EGFR interacts with phospholipase C-gamma
  • EGFR Transactivation by Gastrin
  • Constitutive Signaling by Aberrant PI3K in Cancer
  • Signal transduction by L1
  • Constitutive Signaling by EGFRvIII
  • Inhibition of Signaling by Overexpressed EGFR
  • RAF/MAP kinase cascade
  • ERBB2 Regulates Cell Motility
  • PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
  • ERBB2 Activates PTK6 Signaling
  • Cargo recognition for clathrin-mediated endocytosis
  • Clathrin-mediated endocytosis
  • PTK6 promotes HIF1A stabilization
  • Downregulation of ERBB2 signaling
  • TFAP2 (AP-2) family regulates transcription of growth factors and their receptors
  • Extra-nuclear estrogen signaling
  • NOTCH3 Activation and Transmission of Signal to the Nucleus
  • HCMV Early Events
  • Estrogen-dependent nuclear events downstream of ESR-membrane signaling
  • Signaling by ERBB2 KD Mutants
  • Signaling by ERBB2 ECD mutants
  • Signaling by ERBB2 TMD/JMD mutants
  • Cetuximab
  • Lidocaine
  • Gefitinib
  • Erlotinib
  • Lapatinib
  • Panitumumab
  • Alvocidib
  • IGN311
  • Matuzumab
  • Vandetanib
  • Rindopepimut
  • Canertinib
  • Pelitinib
  • Varlitinib
  • AV-412
  • S-{3-[(4-ANILINOQUINAZOLIN-6-YL)AMINO]-3-OXOPROPYL}-L-CYSTEINE
  • PD-168393
  • Afatinib
  • Osimertinib
  • Necitumumab
  • Foreskin keratinocyte (neonatal)
  • Depatuxizumab mafodotin
  • Icotinib
  • Neratinib
  • Dacomitinib
  • Fostamatinib
  • Zalutumumab
  • Brigatinib
  • Olmutinib
  • Zanubrutinib
  • Abivertinib
  • Choriocarcinoma
  • Gastric cancer
  • Bladder cancer
  • Oral cancer
  • Glioma
  • Laryngeal cancer
  • Cervical cancer
  • Esophageal cancer
ERBB3 erb-b2 receptor tyrosine kinase 3
  • Tucatinib
  • Lethal congenital contractural syndrome (LCCS)
  • Type I diabetes mellitus
ESR1 estrogen receptor 1
  • Nuclear signaling by ERBB4
  • PIP3 activates AKT signaling
  • Constitutive Signaling by Aberrant PI3K in Cancer
  • Nuclear Receptor transcription pathway
  • SUMOylation of intracellular receptors
  • Ovarian tumor domain proteases
  • PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
  • TFAP2 (AP-2) family regulates transcription of growth factors and their receptors
  • RUNX1 regulates estrogen receptor mediated transcription
  • ESR-mediated signaling
  • RUNX1 regulates transcription of genes involved in WNT signaling
  • Regulation of RUNX2 expression and activity
  • Regulation of RUNX2 expression and activity
  • Extra-nuclear estrogen signaling
  • Estrogen-dependent gene expression
  • Diethylstilbestrol
  • Chlorotrianisene
  • Conjugated estrogens
  • Desogestrel
  • Levonorgestrel
  • Progesterone
  • Lindane
  • Raloxifene
  • Toremifene
  • Medroxyprogesterone acetate
  • Testosterone
  • Mitotane
  • Estrone
  • Tamoxifen
  • Hexachlorophene
  • Estradiol
  • Ethynodiol diacetate
  • Dobutamine
  • Clomifene
  • Dienestrol
  • Fulvestrant
  • Norgestimate
  • Ethinylestradiol
  • Melatonin
  • Trilostane
  • Naloxone
  • Fluoxymesterone
  • Estramustine
  • Mestranol
  • Danazol
  • Oxybenzone
  • Allylestrenol
  • Zinc
  • Genistein
  • Prasterone
  • Benzophenone
  • Equilin
  • Compound 19
  • Resveratrol
  • Compound 18
  • Phthalic Acid
  • Pyrazole
  • Stanolone
  • Naringenin
  • Compound 4-D
  • 1-[4-(Octahydro-Pyrido[1,2-a]Pyrazin-2-Yl)-Phenyl]-2-Phenyl-1,2,3,4-Tetrahydro-Isoquinolin-6-Ol
  • Quercetin
  • Afimoxifene
  • 2-Phenyl-1-[4-(2-Piperidin-1-Yl-Ethoxy)-Phenyl]-1,2,3,4-Tetrahydro-Isoquinolin-6-Ol
  • Estriol
  • Estrone sulfate
  • Quinestrol
  • Phenolphthalein
  • Permethrin
  • Ospemifene
  • AP1081
  • Custirsen
  • NP-50301
  • CHF 4227
  • TAS-108
  • Lasofoxifene
  • Arzoxifene
  • Elacestrant
  • Bazedoxifene
  • Methyltestosterone
  • beta-Naphthoflavone
  • 17-METHYL-17-ALPHA-DIHYDROEQUILENIN
  • 4-(2-amino-1-methyl-1H-imidazo[4,5-b]pyridin-6-yl)phenol
  • [5-HYDROXY-2-(4-HYDROXYPHENYL)-1-BENZOFURAN-7-YL]ACETONITRILE
  • 4-[(1S,2S,5S)-5-(HYDROXYMETHYL)-8-METHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL
  • 4-[(1S,2S,5S,9R)-5-(HYDROXYMETHYL)-8,9-DIMETHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL
  • 4-[(1S,2S,5S)-5-(HYDROXYMETHYL)-6,8,9-TRIMETHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL
  • (2R,3R,4S)-3-(4-HYDROXYPHENYL)-4-METHYL-2-[4-(2-PYRROLIDIN-1-YLETHOXY)PHENYL]CHROMAN-6-OL
  • (3AS,4R,9BR)-2,2-DIFLUORO-4-(4-HYDROXYPHENYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL
  • (9ALPHA,13BETA,17BETA)-2-[(1Z)-BUT-1-EN-1-YL]ESTRA-1,3,5(10)-TRIENE-3,17-DIOL
  • (9BETA,11ALPHA,13ALPHA,14BETA,17ALPHA)-11-(METHOXYMETHYL)ESTRA-1(10),2,4-TRIENE-3,17-DIOL
  • 3-CHLORO-2-(4-HYDROXYPHENYL)-2H-INDAZOL-5-OL
  • 3-ETHYL-2-(4-HYDROXYPHENYL)-2H-INDAZOL-5-OL
  • Hexestrol
  • dimethyl (1R,4S)-5,6-bis(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hepta-2,5-diene-2,3-dicarboxylate
  • Erteberel
  • N-[(1R)-3-(4-HYDROXYPHENYL)-1-METHYLPROPYL]-2-(2-PHENYL-1H-INDOL-3-YL)ACETAMIDE
  • (3AS,4R,9BR)-4-(4-HYDROXYPHENYL)-6-(METHOXYMETHYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL
  • 4-[1-allyl-7-(trifluoromethyl)-1H-indazol-3-yl]benzene-1,3-diol
  • 4-(6-HYDROXY-1H-INDAZOL-3-YL)BENZENE-1,3-DIOL
  • DIETHYL (1R,2S,3R,4S)-5,6-BIS(4-HYDROXYPHENYL)-7-OXABICYCLO[2.2.1]HEPT-5-ENE-2,3-DICARBOXYLATE
  • 2-Amino-1-methyl-6-phenylimidazo(4,5-b)pyridine
  • 4-[(1S,2R,5S)-4,4,8-TRIMETHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL
  • (3AS,4R,9BR)-4-(4-HYDROXYPHENYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-9-OL
  • 2-(4-hydroxyphenyl)benzo[b]thiophen-6-ol
  • Tibolone
  • Eugenol
  • Synthetic Conjugated Estrogens, A
  • Synthetic Conjugated Estrogens, B
  • Polyestradiol phosphate
  • Norethynodrel
  • Octocrylene
  • Homosalate
  • Enzacamene
  • Zeranol
  • Ractopamine
  • Gestrinone
  • Propyl Gallate
  • 2-Methoxy-6-{(E)-[(4-methylphenyl)imino]methyl}phenol
  • Testosterone cypionate
  • Testosterone enanthate
  • Testosterone undecanoate
  • Stanolone acetate
  • Estradiol acetate
  • Estradiol benzoate
  • Estradiol cypionate
  • Estradiol dienanthate
  • Estradiol valerate
  • Zinc acetate
  • Zinc chloride
  • Zinc sulfate, unspecified form
  • Estriol tripropionate
  • Fluoroestradiol F-18
ETV1 ETS variant transcription factor 1
  • Ewing's sarcoma
  • Prostate cancer
FBXW11 F-box and WD repeat domain containing 11
  • Activation of NF-kappaB in B cells
  • Downstream TCR signaling
  • Regulation of PLK1 Activity at G2/M Transition
  • FCERI mediated NF-kB activation
  • Dectin-1 mediated noncanonical NF-kB signaling
  • CLEC7A (Dectin-1) signaling
  • NIK-->noncanonical NF-kB signaling
  • MAP3K8 (TPL2)-dependent MAPK1/3 activation
  • Neddylation
  • Antigen processing: Ubiquitination & Proteasome degradation
FOS Fos proto-oncogene, AP-1 transcription factor subunit
  • Oxidative Stress Induced Senescence
  • Senescence-Associated Secretory Phenotype (SASP)
  • FCERI mediated MAPK activation
  • Activation of the AP-1 family of transcription factors
  • Interleukin-4 and Interleukin-13 signaling
  • TP53 Regulates Transcription of DNA Repair Genes
  • Estrogen-dependent gene expression
  • NGF-stimulated transcription
  • NGF-stimulated transcription
  • Estrogen-dependent nuclear events downstream of ESR-membrane signaling
  • Pseudoephedrine
  • Nadroparin
FXYD1 FXYD domain containing ion transport regulator 1
  • Ion homeostasis
  • Ion transport by P-type ATPases
  • Potential therapeutics for SARS
GABRB3 gamma-aminobutyric acid type A receptor subunit beta3
  • Signaling by ERBB4
  • GABA receptor activation
  • GABA receptor activation
  • Lorazepam
  • Ethchlorvynol
  • Enflurane
  • Temazepam
  • Butabarbital
  • Butalbital
  • Phenytoin
  • Etomidate
  • Talbutal
  • Pentobarbital
  • Clobazam
  • Meprobamate
  • Eszopiclone
  • Alprazolam
  • Lindane
  • Metharbital
  • Chlordiazepoxide
  • Amoxapine
  • Adinazolam
  • Lamotrigine
  • Piperazine
  • Ivermectin
  • Medroxyprogesterone acetate
  • Clorazepic acid
  • Acamprosate
  • Midazolam
  • Flurazepam
  • Isoflurane
  • Primidone
  • Halazepam
  • Propofol
  • Propofol
  • Diazepam
  • Oxazepam
  • Triazolam
  • Ethanol
  • Methoxyflurane
  • Memantine
  • Clonazepam
  • Methyprylon
  • Halothane
  • Desflurane
  • Flumazenil
  • Estazolam
  • Sevoflurane
  • Glutethimide
  • Camazepam
  • Delorazepam
  • Flunitrazepam
  • Ethyl loflazepate
  • Cloxazolam
  • Bromazepam
  • Clotiazepam
  • Fludiazepam
  • Ketazolam
  • Prazepam
  • Quazepam
  • Cinolazepam
  • Nitrazepam
  • Prasterone
  • Taurine
  • Fospropofol
  • Brotizolam
  • Stiripentol
  • Etizolam
  • Thiocolchicoside
  • Brexanolone
  • Apalutamide
  • Remimazolam
  • Muscimol
  • Benzodiazepine
  • Pinazepam
  • Medazepam
  • Loprazolam
  • Doxefazepam
  • Lormetazepam
  • Nordazepam
  • Oxazepam acetate
  • Cinazepam
  • Bentazepam
  • Mexazolam
GABRR1 gamma-aminobutyric acid type A receptor subunit rho1
  • GABA receptor activation
  • Lindane
  • Picrotoxin
  • Fludiazepam
GAD1 glutamate decarboxylase 1
  • GABA synthesis
  • GABA synthesis, release, reuptake and degradation
  • MECP2 regulates transcription of genes involved in GABA signaling
  • Pyridoxal phosphate
  • Pyridoxal phosphate
  • Glutamic acid
  • Cerebral palsy
GAD2 glutamate decarboxylase 2
  • GABA synthesis
  • GABA synthesis, release, reuptake and degradation
  • MECP2 regulates transcription of genes involved in GABA signaling
  • Pyridoxal phosphate
  • Glutamic acid
GFAP glial fibrillary acidic protein
  • Nuclear signaling by ERBB4
  • Chaperone Mediated Autophagy
  • Alexander disease
GJA5 gap junction protein alpha 5
  • Gap junction assembly
  • Atrial fibrillation
GJB1 gap junction protein beta 1
  • Oligomerization of connexins into connexons
  • Oligomerization of connexins into connexons
  • Transport of connexins along the secretory pathway
  • Gap junction assembly
  • Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy
GLI1 GLI family zinc finger 1
  • Degradation of GLI1 by the proteasome
  • Degradation of GLI1 by the proteasome
  • Hedgehog 'off' state
  • Hedgehog 'on' state
  • GLI proteins bind promoters of Hh responsive genes to promote transcription
GMFB glia maturation factor beta
GNA13 G protein subunit alpha 13
  • NRAGE signals death through JNK
  • Rho GTPase cycle
  • G alpha (12/13) signalling events
  • Thromboxane signalling through TP receptor
  • Thrombin signalling through proteinase activated receptors (PARs)
  • Thrombin signalling through proteinase activated receptors (PARs)

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