Search Results for: ATXN7

Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
TXNDC11 thioredoxin domain containing 11
UBQLN2 ubiquilin 2
  • Cargo recognition for clathrin-mediated endocytosis
USP22 ubiquitin specific peptidase 22
  • HATs acetylate histones
  • Ub-specific processing proteases
VCP valosin containing protein
  • Translesion Synthesis by POLH
  • HSF1 activation
  • ABC-family proteins mediated transport
  • N-glycan trimming in the ER and Calnexin/Calreticulin cycle
  • Hedgehog ligand biogenesis
  • Hh mutants are degraded by ERAD
  • Defective CFTR causes cystic fibrosis
  • Josephin domain DUBs
  • Ovarian tumor domain proteases
  • Neutrophil degranulation
  • E3 ubiquitin ligases ubiquitinate target proteins
  • Protein methylation
  • Aggrephagy
  • Attachment and Entry
  • Attachment and Entry
  • Phosphoaminophosphonic Acid-Adenylate Ester
  • Phenethyl Isothiocyanate
  • Frontotemporal lobar degeneration (FTLD), including: Pick disease of brain; Frontotemporal dementia (FTD); Ubiquitin-positive frontotemporal dementia (UP-FTD); Progressive supranuclear palsy type 1 (PSNP1); Inclusion body myopathy with early-onset paget disease and frontotemporal dementia (IBMPFD); Frontotemporal dementia, chromosome 3-linked (FTD3)
VWF von Willebrand factor
  • Platelet degranulation
  • Intrinsic Pathway of Fibrin Clot Formation
  • Integrin cell surface interactions
  • Integrin signaling
  • GRB2:SOS provides linkage to MAPK signaling for Integrins
  • p130Cas linkage to MAPK signaling for integrins
  • GP1b-IX-V activation signalling
  • MAP2K and MAPK activation
  • Signaling by moderate kinase activity BRAF mutants
  • Signaling by high-kinase activity BRAF mutants
  • Signaling by BRAF and RAF fusions
  • Paradoxical activation of RAF signaling by kinase inactive BRAF
  • Platelet Adhesion to exposed collagen
  • Platelet Aggregation (Plug Formation)
  • Signaling downstream of RAS mutants
  • Signaling by RAF1 mutants
  • Defective F8 cleavage by thrombin
  • Defective F8 binding to von Willebrand factor
  • Antihemophilic factor, human recombinant
  • Egaptivon pegol
  • Caplacizumab
  • Simoctocog alfa
  • Antihemophilic Factor (Recombinant), PEGylated
  • Susoctocog alfa
  • Efmoroctocog alfa
  • Lonoctocog alfa
  • Moroctocog alfa
  • Hemophilia; Hemophilia A (HEMA); Hemophilia B (HEMB); von Willebrand disease (VWD)

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