PABPC1 - New-wiki

Interactant Symbol	Name	Associated Pathways Hide	Binding Drugs Hide	Associated Diseases Hide
PIN1	peptidylprolyl cis/trans isomerase, NIMA-interacting 1	ISG15 antiviral mechanism RHO GTPases Activate NADPH Oxidases Regulation of TP53 Activity through Phosphorylation PI5P Regulates TP53 Acetylation Negative regulators of DDX58/IFIH1 signaling	Beta-(2-Naphthyl)-Alanine 3,6,9,12,15,18-HEXAOXAICOSANE
PRMT6	protein arginine methyltransferase 6	RMTs methylate histone arginines RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
PXN	paxillin	GAB1 signalosome VEGFA-VEGFR2 Pathway Smooth Muscle Contraction Localization of the PINCH-ILK-PARVIN complex to focal adhesions Regulation of cytoskeletal remodeling and cell spreading by IPP complex components PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases
RACK1	receptor for activated C kinase 1	Regulation of TNFR1 signaling TNFR1-induced NFkappaB signaling pathway TNFR1-mediated ceramide production	Copper
RBM4	RNA binding motif protein 4	Circadian Clock
SREK1	splicing regulatory glutamic acid and lysine rich protein 1
STAU1	staufen double-stranded RNA binding protein 1
SYCP3	synaptonemal complex protein 3	Meiotic synapsis		Azoospermia, including: Azoospermia; Azoospermia due to perturbations of meiosis
SYNCRIP	synaptotagmin binding cytoplasmic RNA interacting protein
TERT	telomerase reverse transcriptase	Telomere Extension By Telomerase Formation of the beta-catenin:TCF transactivating complex	Zidovudine Grn163l Tertomotide	Cri du chat syndrome; Cat cry syndrome; Chromosme 5p deletion syndrome
TOB1	transducer of ERBB2, 1
U2AF1	U2 small nuclear RNA auxiliary factor 1	Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination
WBP4	WW domain binding protein 4	mRNA Splicing - Major Pathway
YWHAG	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma	Activation of BAD and translocation to mitochondria Translocation of SLC2A4 (GLUT4) to the plasma membrane Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane RHO GTPases activate PKNs TP53 Regulates Metabolic Genes Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex AURKA Activation by TPX2 Regulation of localization of FOXO transcription factors

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