|
|
OXNAD1 |
oxidoreductase NAD binding domain containing 1 |
|
|
|
|
|
PBX4 |
PBX homeobox 4 |
|
|
|
|
|
PPP1R11 |
protein phosphatase 1 regulatory inhibitor subunit 11 |
|
|
|
|
|
PSMA1 |
proteasome 20S subunit alpha 1 |
- Activation of NF-kappaB in B cells
- Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
- ER-Phagosome pathway
- Cross-presentation of soluble exogenous antigens (endosomes)
- Autodegradation of Cdh1 by Cdh1:APC/C
- SCF-beta-TrCP mediated degradation of Emi1
- APC/C:Cdc20 mediated degradation of Securin
- APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
- Cdc20:Phospho-APC/C mediated degradation of Cyclin A
- Vpu mediated degradation of CD4
- Vif-mediated degradation of APOBEC3G
- SCF(Skp2)-mediated degradation of p27/p21
- Degradation of beta-catenin by the destruction complex
- Downstream TCR signaling
- Regulation of activated PAK-2p34 by proteasome mediated degradation
- Separation of Sister Chromatids
- FCERI mediated NF-kB activation
- Autodegradation of the E3 ubiquitin ligase COP1
- Regulation of ornithine decarboxylase (ODC)
- ABC-family proteins mediated transport
- AUF1 (hnRNP D0) binds and destabilizes mRNA
- Asymmetric localization of PCP proteins
- Degradation of AXIN
- Degradation of DVL
- Hedgehog ligand biogenesis
- Hh mutants are degraded by ERAD
- Dectin-1 mediated noncanonical NF-kB signaling
- CLEC7A (Dectin-1) signaling
- Degradation of GLI1 by the proteasome
- Degradation of GLI2 by the proteasome
- GLI3 is processed to GLI3R by the proteasome
- Hedgehog 'on' state
- Regulation of RAS by GAPs
- TNFR2 non-canonical NF-kB pathway
- NIK-->noncanonical NF-kB signaling
- Defective CFTR causes cystic fibrosis
- MAPK6/MAPK4 signaling
- UCH proteinases
- Ub-specific processing proteases
- CDT1 association with the CDC6:ORC:origin complex
- Orc1 removal from chromatin
- CDK-mediated phosphorylation and removal of Cdc6
- G2/M Checkpoints
- Ubiquitin Mediated Degradation of Phosphorylated Cdc25A
- Ubiquitin-dependent degradation of Cyclin D
- The role of GTSE1 in G2/M progression after G2 checkpoint
- FBXL7 down-regulates AURKA during mitotic entry and in early mitosis
- RUNX1 regulates transcription of genes involved in differentiation of HSCs
- Regulation of RUNX2 expression and activity
- Regulation of RUNX2 expression and activity
- Regulation of RUNX3 expression and activity
- Regulation of PTEN stability and activity
- Neddylation
- Regulation of expression of SLITs and ROBOs
- Interleukin-1 signaling
- Negative regulation of NOTCH4 signaling
- Antigen processing: Ubiquitination & Proteasome degradation
|
- (3AR,6R,6AS)-6-((S)-((S)-CYCLOHEX-2-ENYL)(HYDROXY)METHYL)-6A-METHYL-4-OXO-HEXAHYDRO-2H-FURO[3,2-C]PYRROLE-6-CARBALDEHYDE
|
|
|
|
PTPN12 |
protein tyrosine phosphatase non-receptor type 12 |
- SHC1 events in ERBB2 signaling
- SHC1 events in ERBB2 signaling
- EGFR downregulation
- Signaling by PDGF
- Downregulation of ERBB2 signaling
- Interleukin-37 signaling
- Constitutive Signaling by Overexpressed ERBB2
|
|
|
|
|
RASSF4 |
Ras association domain family member 4 |
|
|
|
|
|
SH3BP5 |
SH3 domain binding protein 5 |
|
|
|
|
|
SYCE2 |
synaptonemal complex central element protein 2 |
|
|
|
|
|
TREX1 |
three prime repair exonuclease 1 |
- Regulation by TREX1
- IRF3-mediated induction of type I IFN
|
|
- Familial chilblain lupus (FCL); Chilblain lupus erythematosus (CHLE)
- Aicardi-Goutieres Syndrome (AGS)
- Retinal vasculopathy with cerebral leukodystrophy (RVCL)
|
|
|
USHBP1 |
USH1 protein network component harmonin binding protein 1 |
|
|
|
|
|
WASF1 |
WASP family member 1 |
- Regulation of actin dynamics for phagocytic cup formation
- Regulation of actin dynamics for phagocytic cup formation
- VEGFA-VEGFR2 Pathway
- RHO GTPases Activate WASPs and WAVEs
- RHO GTPases Activate WASPs and WAVEs
- FCGR3A-mediated phagocytosis
- FCGR3A-mediated phagocytosis
|
|
|
|
|
WASHC3 |
WASH complex subunit 3 |
|
|
|
|
|
ZDHHC17 |
zinc finger DHHC-type palmitoyltransferase 17 |
|
|
|