FXR1 - New-wiki

Interactant Symbol	Name	Associated Pathways Hide	Binding Drugs Hide	Associated Diseases Hide
MAGOHB	mago homolog B, exon junction complex subunit	Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Regulation of expression of SLITs and ROBOs Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
MCRS1	microspherule protein 1	HATs acetylate histones UCH proteinases DNA Damage Recognition in GG-NER
MFAP1	microfibril associated protein 1	Molecules associated with elastic fibres
PRAM1	PML-RARA regulated adaptor molecule 1
PRPF31	pre-mRNA processing factor 31	mRNA Splicing - Major Pathway		Retinitis pigmentosa (RP)
PRSS23	serine protease 23	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
SRPK2	SRSF protein kinase 2		Adenine Purvalanol Phosphoaminophosphonic Acid-Adenylate Ester
STK16	serine/threonine kinase 16		Fostamatinib
SUFU	SUFU negative regulator of hedgehog signaling	Degradation of GLI1 by the proteasome Degradation of GLI1 by the proteasome Degradation of GLI2 by the proteasome GLI3 is processed to GLI3R by the proteasome Hedgehog 'off' state Hedgehog 'on' state		Basal cell nevus syndrome; Nevoid basal cell carcinoma syndrome; Gorlin syndrome
SYT6	synaptotagmin 6
TBC1D22B	TBC1 domain family member 22B
TCEA2	transcription elongation factor A2
TRPM1	transient receptor potential cation channel subfamily M member 1	TRP channels		Congenital stationary night blindness (CSNB), including: CSNB type 1 (CSNB1); CSNB type 2 (CSNB2); CSNB autosomal dominant (CSNBAD); Oguchi disease/ CSNB Oguchi type (CSNBO)
YES1	YES proto-oncogene 1, Src family tyrosine kinase	Signaling by ERBB2 Signaling by SCF-KIT Signaling by SCF-KIT Regulation of KIT signaling FCGR activation PECAM1 interactions EPH-Ephrin signaling CD28 co-stimulation CTLA4 inhibitory signaling EPHB-mediated forward signaling EPHB-mediated forward signaling EPHA-mediated growth cone collapse EPHA-mediated growth cone collapse EPH-ephrin mediated repulsion of cells RUNX2 regulates osteoblast differentiation Regulation of signaling by CBL Regulation of signaling by CBL FCGR3A-mediated IL10 synthesis FCGR3A-mediated phagocytosis Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants	Dasatinib Fostamatinib
ZMAT2	zinc finger matrin-type 2
ZNF417	zinc finger protein 417	Generic Transcription Pathway
ZNF438	zinc finger protein 438
ZNF71	zinc finger protein 71	Generic Transcription Pathway

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