Search Results for: EXOSC8

80 interactions involving EXOSC8 - exosome component 8 found:

Sort by: Symbol Number of Pathways Number of Drugs Number of Diseases
Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
LSM1 LSM1 homolog, mRNA degradation associated
  • mRNA decay by 5' to 3' exoribonuclease
  • mRNA decay by 5' to 3' exoribonuclease
LSM4 LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated
  • mRNA decay by 5' to 3' exoribonuclease
  • mRNA decay by 5' to 3' exoribonuclease
  • mRNA Splicing - Major Pathway
LSM7 LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated
  • mRNA decay by 5' to 3' exoribonuclease
  • mRNA decay by 5' to 3' exoribonuclease
  • mRNA Splicing - Major Pathway
MACIR macrophage immunometabolism regulator
MKRN1 makorin ring finger protein 1
  • AKT phosphorylates targets in the cytosol
  • Regulation of PTEN stability and activity
  • Antigen processing: Ubiquitination & Proteasome degradation
MORN4 MORN repeat containing 4
MPHOSPH6 M-phase phosphoprotein 6
  • Major pathway of rRNA processing in the nucleolus and cytosol
MTREX Mtr4 exosome RNA helicase
  • Major pathway of rRNA processing in the nucleolus and cytosol
  • mRNA Splicing - Major Pathway
MYOZ1 myozenin 1
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NTAQ1 N-terminal glutamine amidase 1
OTUD4 OTU deubiquitinase 4
PALS2 protein associated with LIN7 2, MAGUK family member
PHF21A PHD finger protein 21A
  • HDACs deacetylate histones
  • Potential therapeutics for SARS
  • Factors involved in megakaryocyte development and platelet production
PIAS2 protein inhibitor of activated STAT 2
  • Activation of anterior HOX genes in hindbrain development during early embryogenesis
POLDIP3 DNA polymerase delta interacting protein 3
  • Transport of Mature mRNA derived from an Intron-Containing Transcript
  • mRNA 3'-end processing
  • RNA Polymerase II Transcription Termination
RASD1 ras related dexamethasone induced 1
RASSF1 Ras association domain family member 1
  • Non-small cell lung cancer
  • Bladder cancer
  • Nasopharyngeal cancer
REL REL proto-oncogene, NF-kB subunit
  • Activation of NF-kappaB in B cells
  • Hodgkin lymphoma
RFC5 replication factor C subunit 5
  • Translesion synthesis by REV1
  • Recognition of DNA damage by PCNA-containing replication complex
  • Translesion Synthesis by POLH
  • Polymerase switching on the C-strand of the telomere
  • Activation of ATR in response to replication stress
  • PCNA-Dependent Long Patch Base Excision Repair
  • Translesion synthesis by POLK
  • Translesion synthesis by POLI
  • Termination of translesion DNA synthesis
  • HDR through Single Strand Annealing (SSA)
  • HDR through Homologous Recombination (HRR)
  • Processing of DNA double-strand break ends
  • Presynaptic phase of homologous DNA pairing and strand exchange
  • Gap-filling DNA repair synthesis and ligation in GG-NER
  • Dual Incision in GG-NER
  • Dual incision in TC-NER
  • Gap-filling DNA repair synthesis and ligation in TC-NER
  • Regulation of TP53 Activity through Phosphorylation
  • Polymerase switching
  • G2/M DNA damage checkpoint

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