Search Results for: TLE3

24 interactions involving TLE3 - TLE family member 3, transcriptional corepressor found:

Sort by: Symbol Number of Pathways Number of Drugs Number of Diseases
Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
SIX2 SIX homeobox 2
SIX3 SIX homeobox 3
  • Holoprosencephaly (HPE)
TCF7L2 transcription factor 7 like 2
  • Formation of the beta-catenin:TCF transactivating complex
  • Formation of the beta-catenin:TCF transactivating complex
  • Deactivation of the beta-catenin transactivating complex
  • Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)
  • Ca2+ pathway
  • Binding of TCF/LEF:CTNNB1 to target gene promoters
  • Repression of WNT target genes
  • Repression of WNT target genes
  • Signaling by TCF7L2 mutants
  • Transcriptional Regulation by VENTX
  • RUNX3 regulates WNT signaling
  • Type II diabetes mellitus
XIAP X-linked inhibitor of apoptosis
  • Activation of caspases through apoptosome-mediated cleavage
  • SMAC (DIABLO) binds to IAPs
  • SMAC (DIABLO) binds to IAPs
  • SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes
  • SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes
  • SMAC, XIAP-regulated apoptotic response
  • Deactivation of the beta-catenin transactivating complex
  • RIPK1-mediated regulated necrosis
  • Regulation of TNFR1 signaling
  • TNFR1-induced NFkappaB signaling pathway
  • Regulation of necroptotic cell death
  • Regulation of PTEN localization
  • Regulation of PTEN stability and activity
  • Regulation of the apoptosome activity
  • 1-[3,3-Dimethyl-2-(2-Methylamino-Propionylamino)-Butyryl]-Pyrrolidine-2-Carboxylic Acid(1,2,3,4-Tetrahydro-Naphthalen-1-Yl)-Amide
  • Dequalinium
  • N-METHYLALANYL-3-METHYLVALYL-4-PHENOXY-N-(1,2,3,4-TETRAHYDRONAPHTHALEN-1-YL)PROLINAMIDE
  • AEG35156
  • Other well-defined immunodeficiency syndromes, including the following seven diseases: Wiskott-Aldrich syndrome; DiGeorge syndrome; Hyper-IgE syndrome; X-linked lymphoproliferative syndrome; Immunodeficiency, Polyendocrinopathy, Enteropathy, X-linked Syndrome (IPEX); Cartilage-Hair Hypoplasia; Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED)

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