Search Results for: NEK1

Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
PTPRD protein tyrosine phosphatase receptor type D
  • Receptor-type tyrosine-protein phosphatases
  • Synaptic adhesion-like molecules
SIRPA signal regulatory protein alpha
  • Cell surface interactions at the vascular wall
  • Signal regulatory protein family interactions
  • Signal regulatory protein family interactions
  • Neutrophil degranulation
TP53BP1 tumor protein p53 binding protein 1
  • SUMOylation of transcription factors
  • Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
  • Nonhomologous End-Joining (NHEJ)
  • Processing of DNA double-strand break ends
  • G2/M DNA damage checkpoint
TSC2 TSC complex subunit 2
  • Macroautophagy
  • Inhibition of TSC complex formation by PKB
  • AKT phosphorylates targets in the cytosol
  • Energy dependent regulation of mTOR by LKB1-AMPK
  • TP53 Regulates Metabolic Genes
  • Constitutive Signaling by AKT1 E17K in Cancer
  • TBC/RABGAPs
  • Lymphangioleiomyomatosis (LAM)
  • Tuberous sclerosis complex (TSC); Bourneville-Pringle disease
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta
  • Activation of BAD and translocation to mitochondria
  • Translocation of SLC2A4 (GLUT4) to the plasma membrane
  • RHO GTPases activate PKNs
  • TP53 Regulates Metabolic Genes
  • Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
  • Phenethyl Isothiocyanate
ZNF350 zinc finger protein 350
  • Generic Transcription Pathway
  • SUMOylation of transcription cofactors

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