Search Results for: MARK3

Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
MAPT microtubule associated protein tau
  • Caspase-mediated cleavage of cytoskeletal proteins
  • Lansoprazole
  • Astemizole
  • Paclitaxel
  • Docetaxel
  • Flortaucipir F-18
  • Amyotrophic lateral sclerosis (ALS); Lou Gehrig's disease
  • Frontotemporal lobar degeneration (FTLD), including: Pick disease of brain; Frontotemporal dementia (FTD); Ubiquitin-positive frontotemporal dementia (UP-FTD); Progressive supranuclear palsy type 1 (PSNP1); Inclusion body myopathy with early-onset paget disease and frontotemporal dementia (IBMPFD); Frontotemporal dementia, chromosome 3-linked (FTD3)
  • Progressive supranuclear palsy (PSP); Steele-Richardson-Olszewski syndrome
MITF melanocyte inducing transcription factor
  • SUMOylation of transcription factors
  • Ocular albinism; Ocular albinism, type I (OA1); Waardenburg syndrome, type II (WS2-OA)
  • Waardenburg syndrome (WS)
  • Malignant melanoma
NOL11 nucleolar protein 11
  • rRNA modification in the nucleus and cytosol
  • Major pathway of rRNA processing in the nucleolus and cytosol
PKP2 plakophilin 2
  • Keratinization
  • Formation of the cornified envelope
  • Arrhythmogenic right ventricular cardiomyopathy (ARVC)
PMPCB peptidase, mitochondrial processing subunit beta
  • Mitochondrial protein import
  • Processing of SMDT1
PNPLA2 patatin like phospholipase domain containing 2
  • Acyl chain remodeling of DAG and TAG
  • Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
  • Post-translational protein phosphorylation
PRKCQ protein kinase C theta
  • Apoptotic cleavage of cellular proteins
  • Effects of PIP2 hydrolysis
  • Downstream TCR signaling
  • Inactivation, recovery and regulation of the phototransduction cascade
  • FCERI mediated NF-kB activation
  • FCERI mediated NF-kB activation
  • Netrin-1 signaling
  • G alpha (z) signalling events
  • RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
  • RAS processing
  • Tamoxifen
  • Staurosporine
  • Phosphonothreonine
  • Dexfosfoserine
  • Fostamatinib
  • Type I diabetes mellitus
SAAL1 serum amyloid A like 1
SFN stratifin
  • Activation of BAD and translocation to mitochondria
  • Translocation of SLC2A4 (GLUT4) to the plasma membrane
  • RHO GTPases activate PKNs
  • TP53 Regulates Metabolic Genes
  • TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest
  • Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
  • Regulation of localization of FOXO transcription factors
TCEA2 transcription elongation factor A2
TTR transthyretin
  • Retinoid cycle disease events
  • The canonical retinoid cycle in rods (twilight vision)
  • Non-integrin membrane-ECM interactions
  • Neutrophil degranulation
  • Retinoid metabolism and transport
  • Amyloid fiber formation
  • Zinc
  • Copper
  • Tafamidis
  • Zinc acetate
  • Zinc chloride
  • Zinc sulfate, unspecified form
  • Familial carpal tunnel syndrome
  • Familial amyloidosis
VPS11 VPS11 core subunit of CORVET and HOPS complexes
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma
  • Activation of BAD and translocation to mitochondria
  • Translocation of SLC2A4 (GLUT4) to the plasma membrane
  • Regulation of PLK1 Activity at G2/M Transition
  • Loss of Nlp from mitotic centrosomes
  • Recruitment of mitotic centrosome proteins and complexes
  • Loss of proteins required for interphase microtubule organization from the centrosome
  • Recruitment of NuMA to mitotic centrosomes
  • Anchoring of the basal body to the plasma membrane
  • RHO GTPases activate PKNs
  • TP53 Regulates Metabolic Genes
  • Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
  • AURKA Activation by TPX2
  • Regulation of localization of FOXO transcription factors
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
  • Activation of BAD and translocation to mitochondria
  • Translocation of SLC2A4 (GLUT4) to the plasma membrane
  • RHO GTPases activate PKNs
  • TP53 Regulates Metabolic Genes
  • Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
  • Regulation of localization of FOXO transcription factors
  • Phenethyl Isothiocyanate
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta
  • Activation of BAD and translocation to mitochondria
  • Translocation of SLC2A4 (GLUT4) to the plasma membrane
  • Deactivation of the beta-catenin transactivating complex
  • Rap1 signalling
  • GP1b-IX-V activation signalling
  • KSRP (KHSRP) binds and destabilizes mRNA
  • Interleukin-3, Interleukin-5 and GM-CSF signaling
  • RHO GTPases activate PKNs
  • TP53 Regulates Metabolic Genes
  • Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
  • NOTCH4 Activation and Transmission of Signal to the Nucleus
  • Negative regulation of NOTCH4 signaling
  • Regulation of localization of FOXO transcription factors
  • Phenethyl Isothiocyanate

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