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CAPN7 |
calpain 7 |
- Degradation of the extracellular matrix
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CCDC57 |
coiled-coil domain containing 57 |
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CCHCR1 |
coiled-coil alpha-helical rod protein 1 |
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CDC37 |
cell division cycle 37, HSP90 cochaperone |
- Signaling by ERBB2
- Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants
- Constitutive Signaling by EGFRvIII
- Regulation of necroptotic cell death
- Downregulation of ERBB2 signaling
- RHOBTB2 GTPase cycle
- Constitutive Signaling by Overexpressed ERBB2
- Drug-mediated inhibition of ERBB2 signaling
- Signaling by ERBB2 KD Mutants
- Resistance of ERBB2 KD mutants to trastuzumab
- Resistance of ERBB2 KD mutants to sapitinib
- Resistance of ERBB2 KD mutants to tesevatinib
- Resistance of ERBB2 KD mutants to neratinib
- Resistance of ERBB2 KD mutants to osimertinib
- Resistance of ERBB2 KD mutants to afatinib
- Resistance of ERBB2 KD mutants to AEE788
- Resistance of ERBB2 KD mutants to lapatinib
- Signaling by ERBB2 ECD mutants
- Signaling by ERBB2 TMD/JMD mutants
- Drug resistance in ERBB2 TMD/JMD mutants
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CDK18 |
cyclin dependent kinase 18 |
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COIL |
coilin |
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CWF19L2 |
CWF19 like cell cycle control factor 2 |
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FAM131C |
family with sequence similarity 131 member C |
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FAM90A1 |
family with sequence similarity 90 member A1 |
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GAS8 |
growth arrest specific 8 |
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GPKOW |
G-patch domain and KOW motifs |
- mRNA Splicing - Major Pathway
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HAUS1 |
HAUS augmin like complex subunit 1 |
- Regulation of PLK1 Activity at G2/M Transition
- Loss of Nlp from mitotic centrosomes
- Recruitment of mitotic centrosome proteins and complexes
- Loss of proteins required for interphase microtubule organization from the centrosome
- Recruitment of NuMA to mitotic centrosomes
- Anchoring of the basal body to the plasma membrane
- AURKA Activation by TPX2
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HDAC1 |
histone deacetylase 1 |
- Transcription of E2F targets under negative control by DREAM complex
- Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1
- G0 and Early G1
- p75NTR negatively regulates cell cycle via SC1
- Formation of the beta-catenin:TCF transactivating complex
- NOTCH1 Intracellular Domain Regulates Transcription
- Downregulation of SMAD2/3:SMAD4 transcriptional activity
- SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
- Constitutive Signaling by NOTCH1 PEST Domain Mutants
- Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
- HDACs deacetylate histones
- Notch-HLH transcription pathway
- Deactivation of the beta-catenin transactivating complex
- ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression
- NoRC negatively regulates rRNA expression
- SUMOylation of chromatin organization proteins
- Repression of WNT target genes
- Repression of WNT target genes
- Regulation of TP53 Activity through Acetylation
- G1/S-Specific Transcription
- RNA Polymerase I Transcription Initiation
- RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
- Regulation of PTEN gene transcription
- Regulation of PTEN gene transcription
- Estrogen-dependent gene expression
- Loss of MECP2 binding ability to 5mC-DNA
- Regulation of MECP2 expression and activity
- MECP2 regulates neuronal receptors and channels
- MECP2 regulates transcription of neuronal ligands
- FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes
- Potential therapeutics for SARS
- Factors involved in megakaryocyte development and platelet production
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- Arsenic trioxide
- Zinc
- Vorinostat
- Belinostat
- Pracinostat
- Romidepsin
- Panobinostat
- Fingolimod
- Mocetinostat
- Abexinostat
- Zinc acetate
- Zinc chloride
- Zinc sulfate, unspecified form
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HDAC2 |
histone deacetylase 2 |
- p75NTR negatively regulates cell cycle via SC1
- NOTCH1 Intracellular Domain Regulates Transcription
- Constitutive Signaling by NOTCH1 PEST Domain Mutants
- Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
- HDACs deacetylate histones
- Notch-HLH transcription pathway
- ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression
- NoRC negatively regulates rRNA expression
- SUMOylation of chromatin organization proteins
- Regulation of TP53 Activity through Acetylation
- RNA Polymerase I Transcription Initiation
- Regulation of PTEN gene transcription
- Regulation of PTEN gene transcription
- Regulation of MECP2 expression and activity
- MECP2 regulates neuronal receptors and channels
- FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes
- EGR2 and SOX10-mediated initiation of Schwann cell myelination
- EGR2 and SOX10-mediated initiation of Schwann cell myelination
- Potential therapeutics for SARS
- Factors involved in megakaryocyte development and platelet production
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- Pravastatin
- Lovastatin
- Theophylline
- Valproic acid
- Simvastatin
- Atorvastatin
- Fluvastatin
- Aminophylline
- Oxtriphylline
- Vorinostat
- Belinostat
- Pracinostat
- Romidepsin
- Panobinostat
- Tixocortol
- Mocetinostat
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KIF9 |
kinesin family member 9 |
- COPI-dependent Golgi-to-ER retrograde traffic
- Kinesins
- Kinesins
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LENG1 |
leukocyte receptor cluster member 1 |
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LGALSL |
galectin like |
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LMO1 |
LIM domain only 1 |
- RUNX1 regulates transcription of genes involved in differentiation of HSCs
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LMO3 |
LIM domain only 3 |
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LNX1 |
ligand of numb-protein X 1 |
- Antigen processing: Ubiquitination & Proteasome degradation
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