HSPD1 - New-wiki

Interactant Symbol	Name	Associated Pathways Hide	Binding Drugs Hide	Associated Diseases Hide
ERG	ETS transcription factor ERG			Ewing's sarcoma Prostate cancer
FAM107A	family with sequence similarity 107 member A
FHIT	fragile histidine triad diadenosine triphosphatase		Adenosine monotungstate Ado-P-Ch2-P-Ps-Ado	Non-small cell lung cancer Small cell lung cancer
H2BC21	H2B clustered histone 21	Recognition and association of DNA glycosylase with site containing an affected pyrimidine Cleavage of the damaged pyrimidine Recognition and association of DNA glycosylase with site containing an affected purine Recognition and association of DNA glycosylase with site containing an affected purine Cleavage of the damaged purine Cleavage of the damaged purine Meiotic synapsis Packaging Of Telomere Ends Pre-NOTCH Transcription and Translation Formation of the beta-catenin:TCF transactivating complex Formation of the beta-catenin:TCF transactivating complex PRC2 methylates histones and DNA Condensation of Prophase Chromosomes Oxidative Stress Induced Senescence Senescence-Associated Secretory Phenotype (SASP) DNA Damage/Telomere Stress Induced Senescence HDACs deacetylate histones HATs acetylate histones HATs acetylate histones SIRT1 negatively regulates rRNA expression ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression NoRC negatively regulates rRNA expression NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression DNA methylation Transcriptional regulation by small RNAs Activation of anterior HOX genes in hindbrain development during early embryogenesis Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 Ub-specific processing proteases Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks Nonhomologous End-Joining (NHEJ) Processing of DNA double-strand break ends Deposition of new CENPA-containing nucleosomes at the centromere G2/M DNA damage checkpoint RNA Polymerase I Promoter Opening RNA Polymerase I Promoter Escape RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function RUNX1 regulates transcription of genes involved in differentiation of HSCs Estrogen-dependent gene expression Meiotic recombination HCMV Early Events HCMV Late Events Transcriptional regulation of granulopoiesis Inhibition of DNA recombination at telomere Amyloid fiber formation
HSPE1	heat shock protein family E (Hsp10) member 1		Phenethyl Isothiocyanate
ITGA3	integrin subunit alpha 3	Basigin interactions Integrin cell surface interactions Integrin cell surface interactions Laminin interactions MET activates PTK2 signaling
ITGB1	integrin subunit beta 1	Elastic fibre formation Fibronectin matrix formation Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Cell surface interactions at the vascular wall Basigin interactions Molecules associated with elastic fibres Integrin cell surface interactions Integrin cell surface interactions Laminin interactions Laminin interactions Syndecan interactions ECM proteoglycans Other semaphorin interactions Signal transduction by L1 Localization of the PINCH-ILK-PARVIN complex to focal adhesions CHL1 interactions RHO GTPases Activate Formins Interleukin-4 and Interleukin-13 signaling Platelet Adhesion to exposed collagen MET activates PTK2 signaling MET interacts with TNS proteins HCMV Early Events Potential therapeutics for SARS	Antithymocyte immunoglobulin (rabbit) MK-0668
KRT31	keratin 31	Keratinization Formation of the cornified envelope
KRT34	keratin 34	Keratinization Formation of the cornified envelope
KRT40	keratin 40	Keratinization Formation of the cornified envelope
KRTAP10-3	keratin associated protein 10-3	Keratinization
KRTAP10-8	keratin associated protein 10-8	Keratinization
KRTAP5-9	keratin associated protein 5-9	Keratinization
LINC01554	long intergenic non-protein coding RNA 1554
LRRK2	leucine rich repeat kinase 2	PTK6 promotes HIF1A stabilization	Fostamatinib	Lewy body dementia (LBD); Dementia with Lewy bodies (DLB) Parkinson's disease (PD)
LZTS2	leucine zipper tumor suppressor 2
MAPK6	mitogen-activated protein kinase 6	MAPK6/MAPK4 signaling	Acetylsalicylic acid Minocycline
MCPH1	microcephalin 1	Condensation of Prophase Chromosomes		Primary microcephaly (MCPH)
NOS1AP	nitric oxide synthase 1 adaptor protein
NOTCH2NLA	notch 2 N-terminal like A

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